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394904

Pentafluoropropionic anhydride

Name: Pentafluoropropionic anhydride
Brand: SIAL

derivatization grade (GC derivatization), LiChropur^™, 99%

Synonym(s):

PFPA, Perfluoropropionic anhydride

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About This Item

Linear Formula:

(CF₃CF₂CO)₂O

CAS Number:

356-42-3

Molecular Weight:

310.05

UNSPSC Code:

23151817

NACRES:

NA.22

PubChem Substance ID:

329755875

EC Number:

206-604-2

Beilstein/REAXYS Number:

1806446

MDL number:

MFCD00000429

Assay:

99%

Form:

liquid

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grade

derivatization grade (GC derivatization)

Quality Level

100

assay

99%

form

liquid

quality

LiChropur^™

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations

technique(s)

gas chromatography (GC): suitable

bp

69-70 °C/735 mmHg (lit.)

density

1.571 g/mL at 25 °C (lit.)

SMILES string

FC(F)(F)C(F)(F)C(=O)OC(=O)C(F)(F)C(F)(F)F

InChI

1S/C6F10O3/c7-3(8,5(11,12)13)1(17)19-2(18)4(9,10)6(14,15)16

InChI key

XETRHNFRKCNWAJ-UHFFFAOYSA-N

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Analytical Reagents

Chromatography & Spectroscopy Reagents

Application

Pentafluoropropionic anhydride (PFPA) was used as derivatization reagent for urine samples to determine the presence of codeine, morphine, 6-monoacetylmorphine, ethylmorphine, and dihydrocodeine using GC-MS in selected ion monitoring (SIM) mode. It was also used to derivatize the dry pericardial fluid sample extracts for quantification of cocaine, benzoylecgonine, and cocaethylene in pericardial fluid using GC-MS.

Learn more in the Product Information

Derivatization reagent used in a GC-MS analysis of stereoisomer content of synthetic peptides. Also used in a GC-MS detection method for synephrine in dietary supplements.

For the preparation of volatile pentafluoropropionyl derivatives of a wide range of compounds, for example, amines and alcohols, for EC/GC.

Packaging

Clear borosilicate glass, high hydrolytic resistance (Type I)

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS05

signalword

Danger

hcodes

H314

pcodes

P280 - P305 + P351 + P338 - P310

Hazard Classifications

Skin Corr. 1B

supp_hazards

EUH014

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Gas-chromatographic separation of stereoisomers of dipeptides.

Ralf Pätzold et al.

Chirality, 18(7), 551-557 (2006-05-10)

Synthetic dipeptides comprising mixtures of enantiomers, diastereomers, or sequential isomers were converted into their N-perfluoroacetyl dipeptide esters (perfluoroacetyl: trifluoroacetyl, pentafluoroacetyl, heptafluorobutyryl; ester: methyl, 1-propyl, 2-propyl, 2,2,2-trifluoroethyl) and analyzed by GC-MS on the chiral stationary phases Chirasil-L-Val and Lipodex-E using helium

A rapid and simple procedure for the determination of synephrine in dietary supplements by gas chromatography-mass spectrometry.

Emilia Marchei et al.

Journal of pharmaceutical and biomedical analysis, 41(4), 1468-1472 (2006-05-16)

A simple and rapid procedure based on gas chromatography-mass spectrometry (GC-MS) is described for determination of synephrine, active principle of Citrus aurantium plant, in solid and liquid dietary supplements. After the addition of 3,4-methylenedioxypropylamphetamine as internal standard (I.S.), a liquid-liquid

Comparison of RapiTest? with Emit? d, au? and GC-MS for the Analysis of Drugs in Urine.

Korte, T., et al.

Journal of Analytical Toxicology, 21, 49-53 (1997)

Validation of a procedure for the gas chromatography-mass spectrometry analysis of cocaine and metabolites in pericardial fluid.

María Teresa Contreras et al.

Journal of analytical toxicology, 31(2), 75-80 (2007-06-01)

A method is described for the simultaneous quantification of cocaine, benzoylecgonine, and cocaethylene in pericardial fluid. Pericardial fluid samples from autopsy casework involving cocaine-related deaths and deaths unrelated to drug abuse were collected. The extraction of cocaine and its metabolites

Determination of cortisol in human plasma by gas chromatography/negative ion chemical ionization/mass spectrometry.

F F Hsu et al.

Analytical biochemistry, 216(2), 401-405 (1994-02-01)

We report an isotope dilution mass spectrometry method using capillary gas chromatography negative ion chemical ionization for the determination of cortisol in human plasma. Cortisol was derivatized with pentafluoropropionic anhydride at room temperature and measured by selected ion monitoring of

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Global Trade Item Number

SKU	GTIN
394904-25ML	04061831982725
394904-100ML	04061837810916
394904-10X1ML	04061831982701
394904-5ML	04061831982749

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