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Merck
CN

41924

Cyanoguanidine

≥95.0% (HPLC), pharmaceutical impurity standard

Synonym(s):

Dicyandiamide, Metformin Related Compound A (USP), Metformin impurity A (PhEur), Cyanoguanidine, Dicyanodiamide

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About This Item

Linear Formula:
NH2C(=NH)NHCN
CAS Number:
461-58-5
Molecular Weight:
84.08
EC Number:
207-312-8
UNSPSC Code:
41116107
PubChem Substance ID:
329756165
Beilstein/REAXYS Number:
605637
MDL number:
MFCD00008066

Key Documents

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InChI key

QGBSISYHAICWAH-UHFFFAOYSA-N

InChI

1S/C2H4N4/c3-1-6-2(4)5/h(H4,4,5,6)

SMILES string

NC(=N)NC#N

grade

analytical standard

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤10.0% related substances, ≤5.0% solvents, ≤5.0% water

mp

208-211 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCBR0160V
BCBQ7552V

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Li-Mei Zhang et al.
The ISME journal, 6(5), 1032-1045 (2011-12-03)
Increasing evidence demonstrated the involvement of ammonia-oxidizing archaea (AOA) in the global nitrogen cycle, but the relative contributions of AOA and ammonia-oxidizing bacteria (AOB) to ammonia oxidation are still in debate. Previous studies suggest that AOA would be more adapted
Enrico Colli et al.
Expert opinion on investigational drugs, 16(7), 999-1007 (2007-06-28)
'Overactive bladder' (OAB) is a syndrome that is characterised by symptoms of urgency, with or without urge urinary incontinence, usually with frequency and nocturia [1] . It is a highly prevalent condition affecting 17% of the general population, with a
F Al-Rimawi
Talanta, 79(5), 1368-1371 (2009-07-29)
A simple, and stability-indicating liquid chromatographic method was developed and validated for the analysis of metformin hydrochloride and its related compound (1-cyanoguanidine) in tablet formulations. Liquid chromatography with a UV detector at a wavelength of 232 nm using a Nova-Pak
Xianglan Li et al.
Chemosphere, 75(10), 1417-1422 (2009-03-10)
A field experiment was conducted to study the effect of timing of joint application of urease inhibitor hydroquinone (HQ) and nitrification inhibitor dicyandiamide (DCD) on N(2)O emission from irrigated lowland rice paddy field. Four treatments including Treatment CK (the control
Hong Nie et al.
Bioorganic & medicinal chemistry letters, 16(21), 5513-5516 (2006-08-29)
A series of N-(2-hydroxy-3-sulfonamidobenzene)-N'-arylcyanoguanidines was prepared. In general, these compounds proved to be potent antagonists of CXCR2 while the selectivity versus CXCR1 ranged from non-selective to >200-fold.
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