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Dodecamethylcyclohexasiloxane

analytical standard

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Synonym(s):
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane
Empirical Formula (Hill Notation):
C12H36O6Si6
CAS Number:
Molecular Weight:
444.92
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥97.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

InChI

1S/C12H36O6Si6/c1-19(2)13-20(3,4)15-22(7,8)17-24(11,12)18-23(9,10)16-21(5,6)14-19/h1-12H3

InChI key

IUMSDRXLFWAGNT-UHFFFAOYSA-N

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General description

Dodecamethylcyclohexasiloxane belonging to the class of cyclic volatile methylsiloxanes is identified as a potent environmental contaminant, most prominently found in biota, biosolid samples, soil, sediment samples, wastewaters, etc. These compounds are used as fragrance carriers or solvents in household products, personal care products, cleaning agents and as precursors in the manufacture of silicone polymers.

Application

Dodecamethylcyclohexasiloxane may be used as an analytical reference standard for the quantification of the analyte in the following:
  • Silicone emulsions using gas chromatography with flame ionization detection (GC-FID).
  • Biota and wastewater samples using gas chromatography coupled to mass spectrometry (GC-MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

195.8 °F - closed cup

Flash Point(C)

91 °C - closed cup


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A practical gas chromatography flame ionization detection method for the determination of octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and dodecamethylcyclohexasiloxane in silicone emulsions
Brothers MH, et al.
Journal of Chromatography A, 144, 116-125 (2016)
Determination of cyclic and linear siloxanes in wastewater samples by ultrasound-assisted dispersive liquid?liquid microextraction followed by gas chromatography?mass spectrometry
Cortada C, et al.
Talanta, 120, 191-197 (2014)
A practical gas chromatography flame ionization detection method for the determination of octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and dodecamethylcyclohexasiloxane in silicone emulsions
Kierkegaard A, et al.
Analytical Chemistry, 82(22), 9573-9578 (2010)

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