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43348

Farnesol

stabilized, analytical standard, mixture of isomers

Synonym(s):

3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol

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About This Item

Linear Formula:
(CH3)2C=CHCH2CH2C(CH3)=CHCH2CH2C(CH3)=CHCH2OH
CAS Number:
4602-84-0
Molecular Weight:
222.37
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329756337
MDL number:
MFCD00002918
Beilstein/REAXYS Number:
1763926
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grade

analytical standard

Quality Level

100

assay

≥95.0% (GC)

shelf life

limited shelf life, expiry date on the label

contains

α-tocopherol (synthetic stabilizer)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.488-1.492, n20/D 1.489 (lit.)

bp

149 °C/4 mmHg (lit.)

density

0.886 g/mL at 20 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

C/C(CC/C=C(C)/CCC=C(C)C)=C\CO

InChI

1S/C15H26O/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16/h7,9,11,16H,5-6,8,10,12H2,1-4H3/b14-9+,15-11+

InChI key

CRDAMVZIKSXKFV-YFVJMOTDSA-N

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General description

Farnesol is a sesquiterpenoid, acting as a quorum-sensing molecule that inhibits filamentation in Candida albicans. It can exhibit chemotherapeutic activity toward pancreatic and other cancers.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

204.8 °F - closed cup

flash_point_c

96.00 °C - closed cup

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM3344
BCCH1415
BCCF0607
BCCC4574
BCBV6303

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Inhibition of Candida albicans Biofilm Formation by Farnesol, a Quorum-Sensing Molecule.
Ramage G, et al.
Applied and Environmental Microbiology, 68(11), 5459?5463-5459?5463 (2002)
Sensitization of Staphylococcus aureus and Escherichia coli to Antibiotics by the Sesquiterpenoids Nerolidol, Farnesol, Bisabolol, and Apritone.
Brehm-Stecher FB and Johnson AE
Antimicrobial Agents and Chemotherapy, 47(10), 3357?3360-3357?3360 (2003)
Effects of the isoprenoids perillyl alcohol and farnesol on apoptosis biomarkers in pancreatic cancer chemoprevention.
DYB, et al.
Anticancer Research, 22(10), 3127-3134 (2002)
Quorum sensing in dimorphic fungi: farnesol and beyond.
Kenneth W Nickerson et al.
Applied and environmental microbiology, 72(6), 3805-3813 (2006-06-06)
Sarah Gilpin et al.
Cutaneous and ocular toxicology, 29(4), 278-287 (2010-09-23)
The fragrance material farnesol is cited as an infrequent but important cause of allergic contact dermatitis (ACD). It is included in the fragrance mix II patch series and requires labeling in the European Union if it is used in a
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Global Trade Item Number

SKUGTIN
43348-1ML04061832109985

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