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437581

Chloroform

ACS reagent, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

Synonym(s):

Methylidyne trichloride, Trichloromethane

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About This Item

Empirical Formula (Hill Notation):
CHCl3
CAS Number:
67-66-3
Molecular Weight:
119.38
PubChem Substance ID:
329756389
UNSPSC Code:
12352101
Beilstein/REAXYS Number:
1731042
MDL number:
MFCD00000826
Assay:
≥99.8%
Grade:
ACS reagent
Bp:
60.5-61.5 °C
Vapor pressure:
160 mmHg ( 20 °C)
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grade

ACS reagent

Quality Level

200

vapor density

4.1 (vs air)

vapor pressure

160 mmHg ( 20 °C)

assay

≥99.8%

form

liquid

contains

0.5-1.0% ethanol as stabilizer

packaging

PVC-coated bottle of 4x4 L

dilution

(for analytical testing)

evapn. residue

≤0.001%

color

APHA: ≤10

refractive index

n20/D 1.445 (lit.)

bp

60.5-61.5 °C

mp

−63 °C (lit.)

density

1.492 g/mL at 25 °C (lit.)

cation traces

Pb: ≤0.05 ppm

SMILES string

ClC(Cl)Cl

InChI

1S/CHCl3/c2-1(3)4/h1H

InChI key

HEDRZPFGACZZDS-UHFFFAOYSA-N

General description

Chloroform is a colorless, volatile chlorinated organic solvent whose vapors have narcotic effect. It is susceptible to degradation with time which can be suppressed by adding ethanol as a stabilizer. Since ethanol is added in higher concentration it leads to increase in polarity which may have a potential influence on some of the applications.
Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs.

Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.

Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.

Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.

Application

Chloroform may be used in the following processes:
  • Synthesis of colloidal hydrophobic CdSe core nanocrystals (quantum dots).
  • Preparing phospholipid solutions.
  • As a solvent in the photolysis reaction of ruthenium complexes.
  • Solvent for recrystallization.
  • As a reference compound to detect the presence of chloroform in tobacco smokes.
  • As an extractant in solvent extraction process.

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
SHBT0749
SHBS4586
SHBN8668
SHBL9875
SHBL9734

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Articles

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Systematic studies on the breakdown of p,p'-DDT in tobacco smokes. Presence of methyl chloride, dichloromethane, and chloroform in tobacco smokes.
Chopra NM and Sherman LR.
Analytical Chemistry, 44(6), 1036-1038 (1972)
Engineering of ultra-small diagnostic nanoprobes through oriented conjugation of single-domain antibodies and quantum dots.
Sukhanova A, et al.
Protocol Exchange (2012)
Eagleson M.
Concise Encyclopedia Chemistry, 216-216 (1994)
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Global Trade Item Number

SKUGTIN
437581-4L04061837566622
437581-4X4L04061837566639