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Merck
CN

43827

4-Aminoantipyrine

analytical standard

Synonym(s):

4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, Ampyrone

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About This Item

Empirical Formula (Hill Notation):
C11H13N3O
CAS Number:
83-07-8
Molecular Weight:
203.24
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329756413
EC Number:
201-452-3
Beilstein/REAXYS Number:
181635
MDL number:
MFCD00003145

Key Documents

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InChI

1S/C11H13N3O/c1-8-10(12)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,12H2,1-2H3

SMILES string

CN1N(c2ccccc2)C(=O)C(N)=C1C

InChI key

RLFWWDJHLFCNIJ-UHFFFAOYSA-N

grade

analytical standard

assay

≥99.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

loss

≤0.5% loss on drying

Quality Level

100

application(s)

environmental
pharmaceutical

format

neat

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General description

4-Aminoantipyrine is a type of non-steroid, anti-inflammatory drug (NSAID). It is a PGE2-dependent blocker and inhibitor of cyclooxygenase (COX).

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM8060
BCCK5671
BCCF9602
BCCF2998
BCBX9195

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4-Aminoantipyrine reduces toxic and genotoxic effects of doxorubicin, cisplatin, and cyclophosphamide in male mice.
Berno CR, et al.
Mutation Research. Genetic Toxicology and Environmental Mutagenesis, 805, 19-24 (2016)
Synthesis of rose like structured LaCoO3 assisted functionalized carbon nanofiber nanocomposite for efficient electrochemical detection of anti-inflammatory drug 4-aminoantipyrine.
Sakthivel M, et al.
Electrochimica Acta, 260, 571-581 (2018)
Xudong Yu et al.
Materials science & engineering. C, Materials for biological applications, 40, 467-471 (2014-05-27)
In this paper, a new kind of phenol-based chemsensor L2 comprised of a Schiff base and azo groups was rationally designed and synthesized. It could selectively recognize fluoride anion among tested anions such as F(-), AcO(-), H2PO4(-), Cl(-), Br(-), and
Saloua Hatmi et al.
Journal of experimental botany, 66(3), 775-787 (2014-11-12)
Environmental factors including drought stress may modulate plant immune responses and resistance to pathogens. However, the relationship between mechanisms of drought tolerance and resistance to pathogens remained unknown. In this study, the effects of drought stress on polyamine (PA) homeostasis
Ildiko Kasza et al.
PLoS genetics, 10(8), e1004514-e1004514 (2014-08-08)
Homeostatic temperature regulation is fundamental to mammalian physiology and is controlled by acute and chronic responses of local, endocrine and nervous regulators. Here, we report that loss of the heparan sulfate proteoglycan, syndecan-1, causes a profoundly depleted intradermal fat layer
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