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Merck
CN

43963

Moxalactam Supplement

suitable for microbiology

Synonym(s):

Listeria MOX Supplement

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About This Item

Empirical Formula (Hill Notation):
C20H20N6O9S
CAS Number:
64952-97-2
Molecular Weight:
520.47
NACRES:
NA.85
PubChem Substance ID:
329756436
UNSPSC Code:
41171614
EC Number:
265-287-9
MDL number:
MFCD00865991

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InChI

1S/C20H20N6O9S/c1-25-19(22-23-24-25)36-8-10-7-35-18-20(34-2,17(33)26(18)13(10)16(31)32)21-14(28)12(15(29)30)9-3-5-11(27)6-4-9/h3-6,12,18,27H,7-8H2,1-2H3,(H,21,28)(H,29,30)(H,31,32)/t12?,18-,20+/m1/s1

InChI key

JWCSIUVGFCSJCK-CAVRMKNVSA-N

SMILES string

CO[C@]2(NC(=O)C(C(O)=O)c1ccc(O)cc1)[C@H]3OCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O

sterility

sterile

form

powder

shelf life

limited shelf life, expiry date on the label

application(s)

environmental
food and beverages, microbiology

storage temp.

2-8°C

suitability

Listeria spp.

Quality Level

100

Related Categories

General description

An antibiotic supplement recommended for selective isolation and cultivation of Listeria monocytogenes.

Application

for selective isolation and cultivation of Listeria monocytogenes

Other Notes

(per vial, sufficient for 1000 ml medium)
Moxalactam 20.0 mg

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7623
BCCL5467
BCCM4077
BCCJ8290
BCCG5972

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J Scott Weese et al.
Anaerobe, 57, 35-38 (2019-03-19)
Clostridium (Clostridioides) difficile has been identified in humans and a wide range of animal species, but there has been little study of remote animal populations with limited human contact. The objective of this study was to determine the prevalence and
Markus Fridén et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 30(1), 150-161 (2009-09-17)
A major challenge associated with the determination of the unbound brain-to-plasma concentration ratio of a drug (K(p,uu,brain)), is the error associated with correction for the drug in various vascular spaces of the brain, i.e., in residual blood. The apparent brain
Dingguo Xu et al.
Journal of the American Chemical Society, 129(35), 10814-10822 (2007-08-19)
Hybrid quantum mechanical/molecular mechanical (QM/MM) methods and density functional theory (DFT) were used to investigate the initial ring-opening step in the hydrolysis of moxalactam catalyzed by the dizinc L1 beta-lactamase from Stenotrophomonas maltophilia. Anchored at the enzyme active site via
Julian R Garneau et al.
Journal of clinical microbiology, 57(5) (2019-02-15)
The epidemiology of Clostridioides difficile infection (CDI) has drastically changed since the emergence of the epidemic strain BI/NAP1/027, also known as ribotype 027 (R027). However, the relationship between the infecting C. difficile strain and clinical outcomes is still debated. We
James Spencer et al.
Journal of the American Chemical Society, 127(41), 14439-14444 (2005-10-13)
Metallo-beta-lactamases are zinc-dependent enzymes responsible for resistance to beta-lactam antibiotics in a variety of host bacteria, usually Gram-negative species that act as opportunist pathogens. They hydrolyze all classes of beta-lactam antibiotics, including carbapenems, and escape the action of available beta-lactamase
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