44578
Dragendorff reagent
for TLC derivatization
SMILES string
[Bi](I)(I)I.[K+].[I-]
InChI
1S/Bi.4HI.K/h;4*1H;/q+3;;;;;+1/p-4
InChI key
ONBIUAZBGHXJDM-UHFFFAOYSA-J
composition
acetic acid , ethyl acetate , sodium iodide , sodium tetraiodobismutate
technique(s)
thin layer chromatography (TLC): suitable
Quality Level
Application
- Nematocidal alkaloids from the roots of Stemona mairei: This study explores the use of Dragendorff reagent for the identification of nematocidal alkaloids, demonstrating its critical role in the pharmacological profiling and characterization of natural products (Shi et al., 2023).
- Rapid Detection and Determination of Scopolamine in Black Henbane: Leveraging Dragendorff reagent, this research developed a novel nanosensor for detecting scopolamine, an important application in pharmaceutical analysis and toxicology (Mousavizadeh et al., 2022).
- Proximate analysis and multi spectrometric analysis of Strychnos nux-vomica nuts: The use of Dragendorff reagent in the multi-spectrometric analysis highlights its versatility in chemical synthesis and compound identification, providing essential insights for medicinal chemistry (Ramachandran et al., 2022).
- TLC-MS identification of alkaloids in Leonuri Herba and Leonuri Fructus: This study used Dragendorff reagent to optimize a universal derivatization method, enhancing the detection and analysis of key pharmaceutical compounds in traditional medicine (Zhang et al., 2021).
- Densitometric TLC analysis for control of tropane and steroidal alkaloids in Lycium barbarum: Demonstrates the application of Dragendorff reagent in food chemistry for ensuring the safety and efficacy of herbal supplements through the precise detection of alkaloids (Kokotkiewicz et al., 2017).
Other Notes
This non-aqueous Thiess, Reuther and Vagujfalvi variant of the reagent is used to detect alkaloids and other nitrogen compounds in TLC
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
target_organs
Central nervous system
Storage Class
3 - Flammable liquids
wgk
WGK 3
flash_point_f
44.6 °F
flash_point_c
7 °C
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Regulatory Information
危险化学品
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Effect of Annona muricata, Abutilon indicum and Evolvulus alsinoides extract on spore germination of sorghum grain mold fungi.
Basha, S. Ameer, A. Sajeli Begum, and G. Raghavendra
International Journal of Bio-resource and Stress Management, 5.1, 102-106 (2014)
W. Funk et al.
J. Planar Chromatogr., 4, 123-123 (1991)
E. Talas et al.
J. Planar Chromatogr., 5, 28-28 (1992)
Feng Qiu et al.
Drug metabolism and disposition: the biological fate of chemicals, 36(11), 2159-2165 (2008-08-16)
The urinary metabolites of berberine, an isoquinoline alkaloid isolated from several Chinese herbal medicines, were investigated in rats and humans. Using macroporous adsorption resin chromatography, open octadecyl silane column chromatography and preparative high-performance liquid chromatography, we isolated seven metabolites (HM1-HM7)
Tensammetric studies of the separation of surfactants: Part 1. Investigation of sources of error in precipitation of non-ionic surfactants with modified Dragendorff reagent.
Wyrwas, Bogdan, Andrzej Szymanski, and Zenon Lukaszewski
Analytica Chimica Acta, 278.1, 197-203 (1993)
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