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Merck
CN

45631

Prochloraz

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C15H16Cl3N3O2
CAS Number:
67747-09-5
Molecular Weight:
376.67
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329756845
EC Number:
266-994-5
Beilstein/REAXYS Number:
8155344
MDL number:
MFCD00078735

Key Documents

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InChI key

TVLSRXXIMLFWEO-UHFFFAOYSA-N

InChI

1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3

SMILES string

CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)n2ccnc2

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

Quality Level

100

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Application

Prochloraz may be used as an analytical reference standard for the quantification of the analyte in agricultural commodities using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Prochloraz belongs to the imidazole class of fungicides, with protective and curative action, found to be effective against different fungi affecting cereal crops, turf, citrus and tropical fruit, field legumes and beet. Its mode of action involves the inhibition of ergosterol biosynthesis.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

农药列管产品
This item has

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP1704
BCCG1684
BCCB7755
BCBW4694

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Simplified determination of combined residues of prochloraz and its metabolites in vegetable, fruit and wheat samples by gas chromatography
Paoli D.M, et al.
Journal of Chromatography A, 765(1), 127-131 (1997)
Nigel C Noriega et al.
Biology of reproduction, 72(6), 1324-1335 (2005-01-28)
Prochloraz (PZ) is an imidazole fungicide that displays multiple endocrine activities. It inhibits steroid synthesis via P450 modulation and acts as an androgen receptor (AR) antagonist, but its effects on male sexual differentiation have not been described. The purpose of
Determination of fungicide residues in fruits and vegetables by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry
Blasco C, et al.
Journal of Chromatography A, 947(2), 227-235 (2002)
Karen L Thorpe et al.
Aquatic toxicology (Amsterdam, Netherlands), 105(3-4), 412-420 (2011-08-13)
Exogenous treatment of fish with natural sex hormones and their mimics has been shown to influence gonadal differentiation resulting in biased phenotypic sex-ratios. This has lead to the development of the Fish Sexual Development Test (FSDT) as a method for
Frederik Knud Nielsen et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(2), 343-350 (2011-12-27)
The effects of three model endocrine disruptors, prochloraz, ketoconazole and genistein on steroidogenesis were tested in the adrenocortical H295R cell line to demonstrate that a broader mechanistic understanding can be achieved in one assay by applying chemical analysis to the
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