46289
Furaltadone
VETRANAL®, analytical standard
Synonym(s):
5-Morpholinomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidinone
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About This Item
Empirical Formula (Hill Notation):
C13H16N4O6
CAS Number:
Molecular Weight:
324.29
Beilstein:
8130725
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
storage temp.
2-8°C
SMILES string
[O-][N+](=O)c1ccc(\C=N\N2CC(CN3CCOCC3)OC2=O)o1
InChI
1S/C13H16N4O6/c18-13-16(14-7-10-1-2-12(22-10)17(19)20)9-11(23-13)8-15-3-5-21-6-4-15/h1-2,7,11H,3-6,8-9H2/b14-7+
InChI key
YVQVOQKFMFRVGR-VGOFMYFVSA-N
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General description
Furaltadone is a nitrofuran drug, with broad-spectrum antimicrobial activity. It is widely used in veterinary medicine for intensive animal production, especially in pigs, poultry, fish and to provide resistance against infections caused by Escherichia coli and Salmonella.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. Furaltadone may be used as an analytical reference standard for the quantification of the analyte in milk samples and poultry eggs using different chromatography techniques.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Determination of nitrofurantoin, furazolidone and furaltadone in milk by high-performance liquid chromatography with electrochemical detection
Diaz G.T, et al.
Analytical Methods : Advancing Methods and Applications, 764(2), 243-248 (1997)
M C Mahedero et al.
Journal of pharmaceutical and biomedical analysis, 29(3), 477-485 (2002-06-14)
An UV spectroscopic method is proposed to analyze mixtures of the nitrofuran derivatives, nitrofurantoin, furaltadone and furazolidone, used in veterinary. The change of absorption spectra due to photo-decomposition is used. A 20% dimethylformamide/water, basic medium of pH 9.4 (ammonium chloride/ammonia)
L P Jager et al.
European journal of pharmacology, 331(2-3), 325-331 (1997-07-23)
Changes in the biogenesis of corticosteroids caused by nitrofurans were studied. The three nitrofurans used: furazolidone, furaltadone and nitrofurantoin, altered the steroid production/release by porcine adrenocortical cells in vitro during 1 h incubations. With pregnenolone as a substrate the nitrofurans
Sara Leston et al.
Chemosphere, 82(7), 1010-1016 (2010-11-27)
The use of pharmaceuticals in the food production industry as prophylatic and therapeutic agents is necessary to promote animal health, but may entail significant consequences to natural ecosystems, especially in the cases of overdosing and use of banned pharmaceuticals. The
Zhen-Lin Xu et al.
Talanta, 103, 306-313 (2012-12-04)
A heterologous competitive indirect enzyme-linked immunosorbent assay (ciELISA) for the determination of the furaltadone metabolite 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ) was developed. AMOZ was derivatised with 2-(4-formylphenoxy) acetic acid or 2-(3-formylphenoxy) acetic acid to obtain two novel immunizing haptens. The ability of these
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