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Merck
CN

46337

17α-Hydroxyprogesterone

VETRANAL®, analytical standard

Synonym(s):

17α-Hydroxy-4-pregnene-3,20-dione, 4-Pregnen-17α-ol-3,20-dione

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About This Item

Empirical Formula (Hill Notation):
C21H30O3
CAS Number:
68-96-2
Molecular Weight:
330.46
EC Number:
200-699-4
UNSPSC Code:
41116107
PubChem Substance ID:
329757144
Beilstein/REAXYS Number:
3218109
MDL number:
MFCD00003659

Key Documents

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Product Name

17α-Hydroxyprogesterone, VETRANAL®, analytical standard

InChI key

DBPWSSGDRRHUNT-CEGNMAFCSA-N

InChI

1S/C21H30O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h12,16-18,24H,4-11H2,1-3H3/t16-,17+,18+,19+,20+,21+/m1/s1

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(C)=O

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardEnvironment
GHS08,GHS09

signalword

Danger

Hazard Classifications

Aquatic Chronic 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCBZ0892

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K Deveci et al.
European review for medical and pharmacological sciences, 17(2), 261-265 (2013-02-05)
Familial Mediterranean Fever (FMF) is an autosomal recessive disease characterized by short lived, febrile serosae inflammatory attacks. FMF has various effects in multiple systems and organs. In the present study, our aim was to evaluate adrenal steroidogenesis in female FMF
Hong Yu et al.
Zhonghua fu chan ke za zhi, 47(9), 651-654 (2012-11-13)
To investigate the clinical features and pregnant outcomes of the pregnant women with congenital adrenal hyperplasia (CAH) 21-hydroxylase deficiency (21-OHD). The clinical features, therapies, pregnant outcomes of the pregnant women with 21-OHD were retrospectively reviewed in Peking Union Medical College
Stefan Németh et al.
Clinica chimica acta; international journal of clinical chemistry, 414, 211-214 (2012-09-19)
Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder most commonly caused by defects in the CYP21A2 gene. Neonatal CAH-screening based on 17-hydroxyprogesterone (17-OHP) measurements prevents life-threatening salt wasting conditions in newborns, but results in a considerable false-positive rate. Therefore
Areana Diogo Nascimento et al.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 29(3), 246-249 (2012-12-01)
To evaluate the relationship between serum anti-Mullerian hormone levels (AMH) and insulin resistance (IR) before and after meformin treatment and to compare AMH levels of polycystic ovary syndrome (PCOS) women in the early follicular phase. Twenty PCOS women with IR
O Lekarev et al.
Journal of perinatology : official journal of the California Perinatal Association, 33(1), 76-78 (2012-12-28)
Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder where steroidogenesis in the adrenal cortex is impaired. The most common form is caused by 21-hydroxylase deficiency (21OHD). Classical 21OHD is characterized by glucocorticoid and mineralocorticoid deficiency and by overproduction of
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