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Merck
CN

46494

Nifuroxazide

VETRANAL®, analytical standard

Synonym(s):

5-Nitro-2-furaldehyde p-hydroxybenzoylhydrazone

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About This Item

Empirical Formula (Hill Notation):
C12H9N3O5
CAS Number:
965-52-6
Molecular Weight:
275.22
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329757202
EC Number:
213-522-0
Beilstein/REAXYS Number:
4264976
MDL number:
MFCD00079482

Key Documents

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InChI key

YCWSUKQGVSGXJO-NTUHNPAUSA-N

InChI

1S/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17)/b13-7+

SMILES string

Oc1ccc(cc1)C(=O)N\N=C\c2ccc(o2)[N+]([O-])=O

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

Quality Level

200

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General description

Nifuroxazide is an oral antibiotic, which may be used for the treatment of diarrhea.

Application

Nifuroxazide may be used as a reference standard in the determination of the analyte in plasma samples using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK3952
BCCF2302
BCBW4413
BCBW1543

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Bernard G Cipolla et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 64(5), 363-368 (2010-01-29)
Reducing polyamine uptake by selecting low polyamine-containing foodstuffs and reducing bacterial gut production can improve performance status and pain control in hormone refractory prostate cancer (HRPC) patients. Long term PRD observance and tolerance were assessed. Cancer specific survival was studied
Fadia H Metwally
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 69(2), 343-349 (2007-07-17)
The quantitative predictive abilities of the new and simple bivariate spectrophotometric method are compared with the results obtained by the use of multivariate calibration methods [the classical least squares (CLS), principle component regression (PCR) and partial least squares (PLS)], using
Rebai Ben Ammar et al.
Chemico-biological interactions, 174(1), 1-10 (2008-05-31)
The effect of extracts obtained from Rhamnus alaternus L. leaves on genotoxicity and SOS response induced by aflatoxin B(1) (10 microg/assay) as well as nifuroxazide (20 microg/assay) was investigated in a bacterial assay system, i.e., the SOS chromotest with Escherichia
JAK-STAT Pathway in Disease (2009)
Akilimali Shindano et al.
Acta gastro-enterologica Belgica, 70(1), 32-33 (2007-07-11)
We report the case of a middle-aged woman who developed a typical picture of acute pancreatitis together with systemic features of immunoallergy after the intake of two capsules (200 mg) of nifuroxazide. Even if acute pancreatitis is a rare adverse
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