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Merck
CN

46702

Pyrantel pamoate

VETRANAL®, analytical standard

Synonym(s):

1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4′-methylenebis(3-hydroxy-2-naphthoic acid), Pyrantel embonate

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About This Item

Linear Formula:
C11H14N2S · C23H16O6
CAS Number:
22204-24-6
Molecular Weight:
594.68
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329756621
EC Number:
244-837-1
Beilstein/REAXYS Number:
9034755
MDL number:
MFCD00072037

Key Documents

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Product Name

Pyrantel pamoate, VETRANAL®, analytical standard

InChI key

AQXXZDYPVDOQEE-MXDQRGINSA-N

InChI

1S/C23H16O6.C11H14N2S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-6,9H,3,7-8H2,1H3/b;6-5+

SMILES string

CN1CCCN=C1\C=C\c2cccs2.OC(=O)c3cc4ccccc4c(Cc5c(O)c(cc6ccccc56)C(O)=O)c3O

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

Quality Level

200

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Pyrantel pamoate may be used as a reference standard in the determination of pyrantel pamoate in dog plasma and veterinary tablets using high performance liquid chromatography (HPLC) and mid-infrared spectroscopy (IR), respectively.

General description

Chemical structure: tetrahydropyrimidine

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN0852
BCCL8627
BCCB3680
BCCB0882

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Chemometric quality inspection control of pyrantel pamoate, febantel and praziquantel in veterinary tablets by mid infrared spectroscopy.
Piantavini S M, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 125, 396-403 (2014)
Determination of fenbendazole, praziquantel and pyrantel pamoate in dog plasma by high-performance liquid chromatography.
Morovjan G, et al.
Journal of Chromatography A, 797(1-2), 237-244 (1998)
Yutong Chen et al.
International journal of oncology, 55(1), 142-156 (2019-05-23)
Matrix metalloproteinase‑1 (MMP1) participates in the metastasis of pancreatic cancer, and its expression can be regulated by endogenous microRNAs (miRs/miRNAs) and exogenous inflammatory factors. Whether miRNAs that potentially modulate MMP1 expression can also attenuate the pro‑metastatic effects of its inducer
Jong-Yil Chai et al.
The Korean journal of parasitology, 48(4), 339-342 (2011-01-15)
Phongsaly Province, located in the northernmost area of Lao PDR, was previously suggested to be endemic for the liver fluke Opisthorchis viverrini infection. To confirm, or rule out, this suggestion, the Phonxay village in the Khoua District, Phongsaly Province, was
Moema A Hausen et al.
Parasitology international, 60(1), 54-58 (2010-10-16)
Giardia lamblia is a pathogenic protozoan presenting as the main characteristic, the trophozoite capacity to adhere in host intestinal epithelium, infecting mammals, including humans. The clinical treatment of this disease is based on metronidazole (Mz) that acts as an alternative
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