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Merck
CN

46702

Pyrantel pamoate

VETRANAL®, analytical standard

Synonym(s):

1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4′-methylenebis(3-hydroxy-2-naphthoic acid), Pyrantel embonate

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About This Item

Linear Formula:
C11H14N2S · C23H16O6
CAS Number:
22204-24-6
Molecular Weight:
594.68
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329756621
EC Number:
244-837-1
Beilstein/REAXYS Number:
9034755
MDL number:
MFCD00072037

Key Documents

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InChI key

AQXXZDYPVDOQEE-MXDQRGINSA-N

InChI

1S/C23H16O6.C11H14N2S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-6,9H,3,7-8H2,1H3/b;6-5+

SMILES string

CN1CCCN=C1\C=C\c2cccs2.OC(=O)c3cc4ccccc4c(Cc5c(O)c(cc6ccccc56)C(O)=O)c3O

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

Quality Level

200

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General description

Chemical structure: tetrahydropyrimidine

Application

Pyrantel pamoate may be used as a reference standard in the determination of pyrantel pamoate in dog plasma and veterinary tablets using high performance liquid chromatography (HPLC) and mid-infrared spectroscopy (IR), respectively.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN0852
BCCL8627
BCCB3680
BCCB0882

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Yutong Chen et al.
International journal of oncology, 55(1), 142-156 (2019-05-23)
Matrix metalloproteinase‑1 (MMP1) participates in the metastasis of pancreatic cancer, and its expression can be regulated by endogenous microRNAs (miRs/miRNAs) and exogenous inflammatory factors. Whether miRNAs that potentially modulate MMP1 expression can also attenuate the pro‑metastatic effects of its inducer
Chemometric quality inspection control of pyrantel pamoate, febantel and praziquantel in veterinary tablets by mid infrared spectroscopy.
Piantavini S M, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 125, 396-403 (2014)
Determination of fenbendazole, praziquantel and pyrantel pamoate in dog plasma by high-performance liquid chromatography.
Morovjan G, et al.
Journal of Chromatography A, 797(1-2), 237-244 (1998)
Education and imaging. Gastrointestinal: ascariasis.
A Suzuki et al.
Journal of gastroenterology and hepatology, 23(11), 1770-1770 (2009-01-06)
Fabrizia Veronesi et al.
Veterinary parasitology, 172(1-2), 164-167 (2010-05-18)
A study was carried out to assess the field efficacy of moxidectin (MOX) against Parascaris equorum in foals. A total of 70 foals from 2 Italian thoroughbred (Farms 1 and 2) stud farms and one trotter stud farm (Farm 3)
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