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46738

Spectinomycin dihydrochloride pentahydrate

Name: Spectinomycin dihydrochloride pentahydrate
Brand: SIAL

VETRANAL^®, analytical standard

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₂₄N₂O₇ · 2HCl · 5H₂O

CAS Number:

22189-32-8

Molecular Weight:

495.35

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329757229

EC Number:

244-554-3

Beilstein/REAXYS Number:

5684150

MDL number:

MFCD00150886

Technical Service

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Properties

grade

analytical standard

Quality Segment

100

product line

VETRANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable

solubility

H₂O: soluble at

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

application(s)

clinical testing

format

neat

mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

Cl[H].Cl[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H][C@@]12O[C@H](C)CC(=O)[C@]1(O)O[C@]3([H])[C@@H](NC)[C@@H](O)[C@@H](NC)[C@H](O)[C@@]3([H])O2

InChI

1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1

InChI key

DCHJOVNPPSBWHK-UXXUFHFZSA-N

Description

General description

Chemical structure: aminoglycoside

Application

Spectinomycin dihydrochloride pentahydrate may be used as a reference standard for the determination of spectinomycin in bovine milk samples by liquid chromatography with electrochemical detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.

Preparation Note

Stock solutions should be prepared at 10 mg/mL in water and filter sterilized.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Solutions can be stored at 2-8°C for several weeks or at -20°C for more extended periods.

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Pictograms

GHS07

Signal Word

Warning

Hazard Codes

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)