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Merck
CN

46745

Spiramycin from Streptomyces sp.

VETRANAL®, analytical standard, mixture of isomers

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About This Item

CAS Number:
E Number:
E710
PubChem Substance ID:
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
232-429-6
MDL number:
Technical Service
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grade

analytical standard

Quality Level

product line

VETRANAL®

quality

mixture of isomers

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

antibiotic activity spectrum

Gram-positive bacteria

application(s)

cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

format

neat

mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C\C=C\C=C\[C@H](OC2CCC(C(C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C

InChI

1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26?,27?,28?,29+,30?,31-,32+,34?,35?,36?,37?,38?,39+,40+,41?,42?,43?/m1/s1

InChI key

ACTOXUHEUCPTEW-JMRHEKERSA-N

General description

Chemical structure: macrolide

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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Verónica Chiappe et al.
Acta odontologica latinoamericana : AOL, 24(1), 115-121 (2011-10-21)
In clinical trials, Spiramycin has shown additional benefit overscaling and root planing on pocket depth reduction, but its effect on periodontal microbiota was evaluated only by darkfield microscopy. Therefore, this study was conducted to determine the effect of Spiramycin administration
Fatma Karray et al.
Journal of bacteriology, 192(21), 5813-5821 (2010-09-08)
Streptomyces ambofaciens synthesizes the macrolide antibiotic spiramycin. The biosynthetic gene cluster for spiramycin has been characterized for S. ambofaciens. In addition to the regulatory gene srmR (srm22), previously identified (M. Geistlich et al., Mol. Microbiol. 6:2019-2029, 1992), three putative regulatory
Halitosis and weight loss in a cat.
Genaro A Coria-Avila et al.
Lab animal, 39(6), 169-170 (2010-05-21)



Global Trade Item Number

SKUGTIN
46745-100MG04061832358147