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Merck
CN

46834

Sulfameter

VETRANAL®, analytical standard

Synonym(s):

5-Methoxysulfadiazine, N1-(5-Methoxypyrimidin-2-yl)sulfanilamide, Sulfamethoxydiazine

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About This Item

Empirical Formula (Hill Notation):
C11H12N4O3S
CAS Number:
651-06-9
Molecular Weight:
280.30
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329757247
EC Number:
211-480-8
Beilstein/REAXYS Number:
621130
MDL number:
MFCD00006067

Key Documents

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InChI key

GPTONYMQFTZPKC-UHFFFAOYSA-N

InChI

1S/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)

SMILES string

COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

Quality Level

200

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General description

Chemical structure: sulfonamide
Sulfameter is a long-acting sulfonamide, which is found to be effective on urinary and respiratory tract infections. It is often used for animal disease treatment and prevention.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfameter may be used as a reference standard in the determination of sulfameter in water samples and natural animal casings using solid phase extraction with high-performance liquid chromatography coupled with an ultraviolet detector (SPR-HPLC-UV).

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ7840
BCCJ7736
BCCF9470
BCCD6687
BCBX3995

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Studies of sulfamethoxydiazine.
Chew HW, et al.
Clinical Pharmacology and Therapeutics, 6(3), 307-315 (1965)
Quantitative analysis of sulfonamide residues in natural animal casings by HPLC.
Sun H, et al.
Chromatographia, 66(5-6), 333-337 (2007)
Analysis of sulfonamides in environmental water samples based on magnetic mixed hemimicelles solid-phase extraction coupled with HPLC-UV detection.
Sun L, et al.
Chemosphere, 77(10), 1306-1312 (2009)
I U Asuzu et al.
Biochemical medicine and metabolic biology, 39(2), 158-167 (1988-04-01)
The interactions of aflatoxin B1 (AFB1) with vitamin K, phenylbutazone, and sulfamethoxine were investigated in albino rats. Vitamin K (5 mg/kg) was able to completely suppress the increase in whole blood clotting time caused by AFB1 (25 micrograms/kg). Phenylbutazone (50
Identification of polymorphs of sulfamethoxydiazine by optical and morphological methods.
T Yokoyama et al.
Chemical & pharmaceutical bulletin, 26(4), 1044-1048 (1978-04-01)
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