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Merck
CN

46995

Xylazine hydrochloride

VETRANAL®, analytical standard

Synonym(s):

2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine hydrochloride, 5,6-Dihydro-2-(2,6-xylidino)-4H-1,3-thiazine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H16N2S · HCl
CAS Number:
Molecular Weight:
256.79
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6448471
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InChI

1S/C12H16N2S.ClH/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;/h3,5-6H,4,7-8H2,1-2H3,(H,13,14);1H

SMILES string

Cl[H].Cc1cccc(C)c1NC2=NCCCS2

InChI key

QYEFBJRXKKSABU-UHFFFAOYSA-N

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical
forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

α2-Adrenergic receptor agonist, sedative, muscle relaxant.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

监管及禁止进口产品
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Henry P Farhoodi et al.
Journal of bone oncology, 23, 100298-100298 (2020-07-10)
Many cancers metastasize to the bones, particularly in cases of breast and prostate cancers. Due to the "vicious cycle" of cancer cells inducing bone resorption, which promotes further tumor growth, they are difficult to treat and may lead to extreme
Ori Furman et al.
Theriogenology, 82(8), 1165-1172 (2014-09-13)
This study establishes an experimental model for subclinical mastitis induced by Gram-positive (G+) exosecretions of Staphylococcus aureus origin or Gram-negative (G-) endotoxin of Escherichia coli origin to examine its effects on follicular growth and steroid concentrations in Holstein dairy cows.
Javier Gutiérrez-Cuesta et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(13), 2974-2988 (2014-06-20)
The repeated cycles of cessation of consumption and relapse remain the major clinical concern in treating drug addiction. The endogenous opioid system is a crucial component of the reward circuit that participates in the adaptive changes leading to relapse in
Marzia Ferretti et al.
Histology and histopathology, 29(8), 1027-1037 (2014-02-11)
The present paper completes our recent study on the effects of phytoestrogen ferutinin in preventing osteoporosis and demonstrating the superior osteoprotective effect of a 2 mg/kg/day dose in ovariectomized (OVX) rats, compared to both estrogens and lower (0.5, 1 mg/kg/day)
Burak Turgut et al.
Clinical & experimental ophthalmology, 43(1), 67-76 (2014-05-08)
To investigate the effects of subconjunctivally administered trastuzumab on wound healing in experimental glaucoma filtration surgery. Comparative, experimental study. Twenty eight eyes. Twenty-eight male New Zealand white rabbits were randomly assigned to four groups, each including seven rabbits: The rabbits

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