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Merck
CN

47620

Folic acid

≥97.0% (HPLC)

Synonym(s):

PteGlu, Pteroyl-L-glutamic acid, Vitamin M

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About This Item

Empirical Formula (Hill Notation):
C19H19N7O6
CAS Number:
Molecular Weight:
441.40
EC Number:
200-419-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
100781
MDL number:
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assay

≥97.0% (HPLC)

optical activity

[α]20/D +20±2°, c = 1% in 0.1 M NaOH

impurities

~8% water

ign. residue

≤0.1% (as SO4)

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤1500 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

storage temp.

2-8°C

SMILES string

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

InChI

1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

InChI key

OVBPIULPVIDEAO-LBPRGKRZSA-N

Other Notes

The biochemistry of folates. Reviews


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Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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T. Brody et al.
Food Sci. Technol., 13, 459-459 (1984)
R.L. Kisliuk
Folate Antagonists Ther. Agents, 1, 1-1 (1984)
Thommey P Thomas et al.
Journal of medicinal chemistry, 48(11), 3729-3735 (2005-05-27)
The cellular uptake and cytotoxicity of an engineered multifunctional dendritic nanodevice containing folic acid (FA) as the targeting molecule, methotrexate (MTX) as the chemotherapeutic drug, and fluorescein (FI) as the detecting agent were studied in vitro. FI and FA were