48975
Gliotoxin from Gliocladium fimbriatum
≥98.0% (TLC)
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About This Item
Empirical Formula (Hill Notation):
C13H14N2O4S2
CAS Number:
Molecular Weight:
326.39
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
50675
MDL number:
assay
≥98.0% (TLC)
solubility
chloroform: 10 mg/mL, clear, colorless
antibiotic activity spectrum
viruses
mode of action
DNA synthesis | interferes, enzyme | inhibits
storage temp.
2-8°C
SMILES string
CN1C(=O)[C@]23CC4=CC=C[C@H](O)[C@H]4N2C(=O)[C@@]1(CO)SS3
InChI
1S/C13H14N2O4S2/c1-14-10(18)12-5-7-3-2-4-8(17)9(7)15(12)11(19)13(14,6-16)21-20-12/h2-4,8-9,16-17H,5-6H2,1H3/t8-,9-,12+,13+/m0/s1
InChI key
FIVPIPIDMRVLAY-RBJBARPLSA-N
General description
Chemical structure: epipolythiodioxopiperazine
Application
Noncompetitive inhibitor of the chymotrypsin-like activity of the 20S proteasome in vitro.
Other Notes
Antiphagocytic and immunomodulating agent which acts by blocking membrane thiol groups
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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