50553
α-Tri-Calcium phosphate
Reagent for transient & stable DNA transfections
Synonym(s):
α-TCP, α-Tricalcium phosphate
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About This Item
Linear Formula:
Ca3(PO4)2
CAS Number:
Molecular Weight:
310.18
EC Number:
MDL number:
UNSPSC Code:
41106502
PubChem Substance ID:
NACRES:
NA.52
grade
Molecular Biology
Quality Level
form
powder
technique(s)
transfection: suitable
application(s)
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
storage temp.
room temp
SMILES string
[Ca++].[Ca++].[Ca++].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O
InChI
1S/3Ca.2H3O4P/c;;;2*1-5(2,3)4/h;;;2*(H3,1,2,3,4)/q3*+2;;/p-6
InChI key
QORWJWZARLRLPR-UHFFFAOYSA-H
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General description
α-tri-Calcium is a tasteless powder containing excess of calcium oxide. It is commonly used to introduce DNA and transfect eukaryotic cells for molecular biology experiments.
α-tri-Calcium phosphate (α-TCP) can be made by heating the low-temperature polymorph β-TCP. It can also be made by thermal crystallization of amorphous precursors with the appropriate composition above the transformation temperature. α-TCP is biocompatible as β-TCP. It is highly soluble and hydrolyses quickly to calcium-deficient hydroxyapatite. This makes α-TCP a beneficial constituent for formulating self-setting osteotransductive bone cements and biodegradable bioceramics and composites for bone repairing.
Application
For analysis of bone cement; as standard.
α-tri-Calcium phosphate has been used to transfect 293T and 231 cells with the PiggyBac LSS-mOrange- aspartate-glutamate-valine-aspartate (DEVD)-mKate2 transposon vector and in reporter verification studies.
α-tri-Calcium phosphate has been used to transfect 293T and 231 cells with the PiggyBac LSS-mOrange- aspartate-glutamate-valine-aspartate (DEVD)-mKate2 transposon vector and in reporter verification studies.
Suitable for
- transient and stable transfection of wide range of cell types
- drug delivery systems
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Buschhaus J, et al.
Cells, 7(6), 57-57 (2018)
alpha-Tricalcium phosphate: Synthesis, properties and biomedical applications
Carrodeguas R G and De A S
Acta Biomaterialia, 7(10), 3536-3546 (2011)
Michael D Weiden et al.
PloS one, 9(10), e108476-e108476 (2014-10-02)
While exploring the effects of aerosol IFN-γ treatment in HIV-1/tuberculosis co-infected patients, we observed A to G mutations in HIV-1 envelope sequences derived from bronchoalveolar lavage (BAL) of aerosol IFN-γ-treated patients and induction of adenosine deaminase acting on RNA 1
S I Roohani-Esfahani et al.
Acta biomaterialia, 8(11), 4162-4172 (2012-07-31)
This is the first reported study to prepare highly porous baghdadite (Ca₃ZrSi₂O₉) scaffolds with and without surface modification and investigate their ability to repair critical-sized bone defects in a rabbit radius under normal load. The modification was carried out to
Françoise Borcard et al.
Journal of medicinal chemistry, 55(18), 7988-7997 (2012-08-18)
To control the selective adhesion of human endothelial cells and human serum proteins to bioceramics of different compositions, a multifunctional ligand containing a cyclic arginine-glycine-aspartate (RGD) peptide, a tetraethylene glycol spacer, and a gallate moiety was designed, synthesized, and characterized.
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