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Merck
CN

50956

Stevioside

analytical standard

Synonym(s):

(4α)-13-[(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid β-D-glucopyranosyl ester, Steviosin

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About This Item

Empirical Formula (Hill Notation):
C38H60O18
CAS Number:
Molecular Weight:
804.87
NACRES:
NA.24
UNSPSC Code:
85151701
EC Number:
260-975-5
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InChI key

UEDUENGHJMELGK-HYDKPPNVSA-N

InChI

1S/C38H60O18/c1-16-11-37-9-5-20-35(2,7-4-8-36(20,3)34(50)55-32-29(49)26(46)23(43)18(13-40)52-32)21(37)6-10-38(16,15-37)56-33-30(27(47)24(44)19(14-41)53-33)54-31-28(48)25(45)22(42)17(12-39)51-31/h17-33,39-49H,1,4-15H2,2-3H3/t17-,18-,19-,20+,21+,22-,23-,24-,25+,26+,27+,28-,29-,30-,31+,32+,33+,35-,36-,37-,38+/m1/s1

SMILES string

C[C@@]12CCC[C@](C)([C@H]1CC[C@]34CC(=C)[C@](CC[C@@H]23)(C4)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O

grade

analytical standard

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤12.0% water (Karl Fischer)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

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General description

Component of stevia.
Stevioside is a diterpene glycoside, naturally extracted from the leaves of Stevia rebaudiana Bertoni plant, which can find wide applications as a commercial non-caloric sweetener and can also be used in the treatment of diabetes.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study
Hsieh HM, et al.
Clinical Therapeutics, 25, 2797-2808 (2003)
Stevioside
Guens C.MJ
Phytochemistry, 64, 913-921 (2003)
Kumiko Takahashi et al.
Toxicology mechanisms and methods, 22(4), 243-249 (2012-02-10)
In the laboratory, using a PC12 cell system, studies have been conducted on the effects of various chemicals on apoptosis, as it is considered to be an essential part of normal development, maintenance, and defense in organisms. Stevioside is a
Sha Li et al.
Food chemistry, 138(2-3), 2064-2069 (2013-02-16)
Stevioside is an abundant sweetener extracted from Stevia rebaudiana leaf with a bitter aftertaste. Enzymatic transglycosylation of stevioside is a solution to improve the edulcorant quality of stevioside, but highly derivatised stevioside coming with high conversion of stevioside is undesired.
Munish Puri et al.
Biotechnology advances, 29(6), 781-791 (2011-07-06)
Stevioside is a natural sweetener extracted from leaves of Stevia rebaudiana Bertoni, which is commercially produced by conventional (chemical/physical) processes. This article gives an overview of the stevioside structure, various analysis technique, new technologies required and the advances achieved in

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