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52063

Supelco

Cadaverine

analytical standard

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Synonym(s):
1,5-Diaminopentane, 1,5-Pentanediamine, Pentamethylenediamine
Linear Formula:
NH2(CH2)5NH2
CAS Number:
462-94-2
Molecular Weight:
102.18
Beilstein:
1697256
EC Number:
207-329-0
MDL number:
MFCD00008239
PubChem Substance ID:
329757785
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥96.5% (GC)
96.5-103.5% (T)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤1.5% water

refractive index

n20/D 1.457-1.459
n20/D 1.458 (lit.)

bp

178-180 °C (lit.)

mp

14-16 °C (lit.)

density

0.873 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

format

neat

SMILES string

NCCCCCN

InChI

1S/C5H14N2/c6-4-2-1-3-5-7/h1-7H2

InChI key

VHRGRCVQAFMJIZ-UHFFFAOYSA-N

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General description

Cadaverine, a biogenic amine, belongs to the class of aliphatic diamines and is commonly found in food products including cheese, fish products, fermented sausages, fish sauces, etc. It can be used as a freshness marker and as an indicator of microbial spoilage since it is most commonly identified in food products as a result of inappropriate storage conditions and microbial contamination.

Application

Cadaverine may be used as an analytical reference standard for the quantification of the analyte in:
  • Food samples using an electrochemical disposable screen-printed device consisting of two working electrodes in array mode and reversed-phase high-pressure liquid chromatography with fluorescence detection (HPLC-FLD).
  • Biological matrices using reversed-phase liquid chromatography separation coupled to electrospray ionization-ion trap tandem mass spectrometry (HPLC-ESI-ITMS/MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

143.6 °F - closed cup

Flash Point(C)

62 °C - closed cup

Regulatory Information

危险化学品

Certificates of Analysis (COA)

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Simultaneous determination of cadaverine and putrescine using a disposable monoamine oxidase based biosensor
Henao-Escobar W, et al.
Talanta, 117, 405-411 (2013)
Dietary exposure assessment of putrescine and cadaverine and derivation of tolerable levels in selected foods consumed in Austria
Rauscher-Gabernig E, et al.
European Food Research and Technology, 235(2), 209-220 (2012)
Determination of putrescine, cadaverine, spermidine and spermine in different chemical matrices by high performance liquid chromatography?electrospray ionization?ion trap tandem mass spectrometry (HPLC?ESI?ITMS/MS).
Ibarra A A G, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1002, 176-184 (2015)
Yingjia Li et al.
Pharmaceutical research, 31(8), 2054-2064 (2014-02-22)
The complementary strategy by combining targeting ligand-mediated selectivity and CPP-mediated transmembrane function could be exploit synergies for enhancing cellular uptake of nanoparticles with negative charge. A heparin-based nanoparticles with negative charge was fabricated by complementary strategy, which was expected to
Seiji Kojima et al.
Journal of nutritional science and vitaminology, 58(3), 153-160 (2012-08-11)
Polyamine is a small organic polycation composed of a hydrocarbon backbone with multiple amino groups which ubiquitously exists in all living organisms from bacteria to higher animals. The critical step of polyamine biosynthesis generally includes the amino acid-decarboxylating reaction to
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Protocols

HPLC Analysis of Biogenic Amines on Ascentis® RP-Amide

HPLC Analysis of Biogenic Amines on Ascentis® RP-Amide

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