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Merck
CN

522082

Trichloroacetic acid

biotech. grade, redistilled, ≥99%

Synonym(s):

TCA

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About This Item

Linear Formula:
Cl3CCOOH
CAS Number:
Molecular Weight:
163.39
EC Number:
200-927-2
UNSPSC Code:
12352101
PubChem Substance ID:
Beilstein/REAXYS Number:
970119
MDL number:
Assay:
≥99%
Grade:
biotech. grade
Bp:
196 °C (lit.)
Vapor pressure:
1 mmHg ( 51 °C)
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grade

biotech. grade

vapor density

<1 (vs air)

vapor pressure

1 mmHg ( 51 °C)

assay

≥99%

refractive index

n20/D 1.62 (lit.)

bp

196 °C (lit.)

mp

54-58 °C (lit.)

density

1.62 g/mL at 25 °C (lit.)

SMILES string

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

Application

Suitable for protein sequencing
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

Other Notes

A -D suffix exists for administrative purposes only.
All -D packages are 100% the same product, same quality, same specification as the package sizes previously sold without a -D.


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pictograms

CorrosionEnvironment

signalword

Danger

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

Storage Class

8B - Non-combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Trichloroacetic acid peels.
Nguyen TH and Rooney JA.
Dermatologic Therapy, 13(2), 173-182 (2000)
Trichloroacetic acid at 105 K.
Rajagopal K, et al.
Acta Crystallographica Section E, Structure Reports Online, 59(3), 316-318 (2003)
S L Herren-Freund et al.
Toxicology and applied pharmacology, 90(2), 183-189 (1987-09-15)
Trichloroethylene (TCE) has previously been shown to be carcinogenic in mouse liver when administered by daily gavage in corn oil. The metabolism of TCE results, in part, in the formation of trichloroacetic acid (TCA) as a major metabolite and dichloroacetic