55443
Fenofibrate
analytical standard
Synonym(s):
2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester
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About This Item
Empirical Formula (Hill Notation):
C20H21ClO4
CAS Number:
Molecular Weight:
360.83
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
256-376-3
MDL number:
grade
analytical standard
Quality Level
assay
≥99.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤0.3% water
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c2ccc(Cl)cc2
InChI
1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
InChI key
YMTINGFKWWXKFG-UHFFFAOYSA-N
Gene Information
human ... PPARA(5465)
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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signalword
Warning
hcodes
pcodes
Hazard Classifications
STOT RE 2 Oral
target_organs
Liver
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Fenofibrate: a new treatment for diabetic retinopathy. Molecular mechanisms and future perspectives.
Rafael Simó et al.
Current medicinal chemistry, 20(26), 3258-3266 (2013-06-12)
Despite improving standards of care, people with diabetes remain at risk of development and progression of diabetic retinopathy (DR) and visual impairment. Identifying novel therapeutic approaches, preferably targeting more than one pathogenic pathway in DR, and at an earlier stage
Jonathan E Noonan et al.
Diabetes, 62(12), 3968-3975 (2013-11-23)
The drug fenofibrate has received major attention as a novel medical treatment for diabetic retinopathy (DR) and other diabetes-induced microvascular complications. This interest stems from two recent large, well-designed clinical trials that demonstrated large reductions in the progression of DR
Samuel Rommelaere et al.
PloS one, 9(8), e104925-e104925 (2014-08-21)
Liver is a major regulator of lipid metabolism and adaptation to fasting, a process involving PPARalpha activation. We recently showed that the Vnn1 gene is a PPARalpha target gene in liver and that release of the Vanin-1 pantetheinase in serum
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 55443-100MG | 04061832582405 |