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556416

New Methylene Blue N

Name: New Methylene Blue N
Brand: SIAL

Dye content ~70 %

Synonym(s):

Basic Blue 24, Methylene Blue N

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₂ClN₃S

CAS Number:

1934-16-3

Molecular Weight:

347.91

UNSPSC Code:

12171500

NACRES:

NA.47

PubChem Substance ID:

24879556

EC Number:

217-696-9

Colour Index Number:

52030

MDL number:

MFCD00135878

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Properties

form

powder, crystals or chunks

composition

Dye content, ~70%

technique(s)

microbe id | staining: suitable

mp

190 °C (dec.) (lit.)

λ_max

590 nm, 632 nm (2nd)

ε_max

≥29000 at 626-634 nm in water, ≥30500 at 586-594 nm in water

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Cl-].CCNc1cc2[s+]c3cc(NCC)c(C)cc3nc2cc1C

InChI

1S/C18H22N3S.ClH/c1-5-19-13-9-17-15(7-11(13)3)21-16-8-12(4)14(20-6-2)10-18(16)22-17;/h7-10,19-20H,5-6H2,1-4H3;1H/q+1;/p-1

InChI key

NZYCYASKVWSANA-UHFFFAOYSA-M

Description

Application

New methylene blue N has been used as a photosensitizer for the photodynamic inactivation of Candida albicans.

Biochem/physiol Actions

New methylene blue N can bind, neutralize and crosslink with RNA. This causes co-precipitation of ribosomal and residual RNA with the mitochondria and ferritin masses. These events make the living young erythrocytes as microscopically visible, dark-blue clusters and filaments, referred to as reticulum. New Methylene Blue N helps in counting of reticulocytes (erythrocytes containing RNA).

Features and Benefits

Solvent soluble cationic thiazine dye

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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