556416
New Methylene Blue N
Dye content ~70 %
Synonym(s):
Basic Blue 24, Methylene Blue N
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About This Item
Empirical Formula (Hill Notation):
C18H22ClN3S
CAS Number:
Molecular Weight:
347.91
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
217-696-9
Colour Index Number:
52030
MDL number:
form
powder, crystals or chunks
composition
Dye content, ~70%
technique(s)
microbe id | staining: suitable
mp
190 °C (dec.) (lit.)
λmax
590 nm, 632 nm (2nd)
εmax
≥29000 at 626-634 nm in water, ≥30500 at 586-594 nm in water
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
[Cl-].CCNc1cc2[s+]c3cc(NCC)c(C)cc3nc2cc1C
InChI
1S/C18H22N3S.ClH/c1-5-19-13-9-17-15(7-11(13)3)21-16-8-12(4)14(20-6-2)10-18(16)22-17;/h7-10,19-20H,5-6H2,1-4H3;1H/q+1;/p-1
InChI key
NZYCYASKVWSANA-UHFFFAOYSA-M
Application
New methylene blue N has been used as a photosensitizer for the photodynamic inactivation of Candida albicans.
Biochem/physiol Actions
New methylene blue N can bind, neutralize and crosslink with RNA. This causes co-precipitation of ribosomal and residual RNA with the mitochondria and ferritin masses. These events make the living young erythrocytes as microscopically visible, dark-blue clusters and filaments, referred to as reticulum. New Methylene Blue N helps in counting of reticulocytes (erythrocytes containing RNA).
Features and Benefits
Solvent soluble cationic thiazine dye
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Fernando A Castro et al.
Veterinary surgery : VS, 34(6), 539-542 (2005-12-14)
To evaluate the accuracy of a new technique for perineural injection of the lateral palmar nerve and to determine frequency of inadvertent injection into the carpal synovial sheath with this technique. Prospective experimental study. Thirty equine cadaver forelimbs. Each of
M Wainwright et al.
Journal of chemotherapy (Florence, Italy), 13(5), 503-509 (2002-01-05)
The antibacterial activities of Methylene Blue and several of its congeners were measured against Yersinia enterocolitica, a gram-negative pathogen known to exhibit significant growth at 4 degrees C and thus constituting a threat to red blood cell concentrates which are
J O'Neill et al.
Journal of chemotherapy (Florence, Italy), 15(4), 329-334 (2003-09-10)
In order to establish a comparative order of efficacy among established photosensitising compounds currently under investigation, the in vitro photobactericidal activities of six commercially available photosensitisers were investigated at equal concentration against Streptococcus sanguis using a Helium Neon (HeNe) laser
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 556416-10G | 04061832582733 |
| 556416-1G | 04061832582740 |