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Merck
CN

55736

Orientin

analytical standard

Synonym(s):

8-β-D-Glucopyranosyl-3′,4′,5,7-tetrahydroxyflavone, Luteolin 8-C-β-D-glucopyranoside, Luteolin-8-glucoside, Lutexin

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About This Item

Empirical Formula (Hill Notation):
C21H20O11
CAS Number:
28608-75-5
Molecular Weight:
448.38
UNSPSC Code:
85151701
PubChem Substance ID:
329758152
MDL number:
MFCD00017432

Key Documents

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InChI

1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc(O)c3C(=O)C=C(Oc23)c4ccc(O)c(O)c4

InChI key

PLAPMLGJVGLZOV-VPRICQMDSA-N

grade

analytical standard

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤5.0% water

application(s)

food and beverages

format

neat

Quality Level

100

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General description

Orientin is a flavone existing in a variety of plants and exhibits a broad-spectrum of pharmacological properties such as free-radical inhibition, antiviral, radioprotection, anti-oxidant and vasorelaxant property.

Application

Orientin may be used as an analytical reference standard for the quantification of the analyte in leaves of Cecropia species and biological samples using various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Flavonoid glycoside found in the acai tree and globe and passion flowers. Antiviral, antimicrobial and antioxidant. Exhibits radioprotective activities.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ5112
BCCJ0619
BCCH0758
BCCG4401
BCCF8113

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Determination and pharmacokinetics of orientin in rabbit plasma by liquid chromatography after intravenous administration of orientin and Trollius chinensis Bunge extract
Li X, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 853(1-2), 221-226 (2007)
An HPLC-DAD method to quantification of main phenolic compounds from leaves of Cecropia species
Costa.MG, et al.
Journal of the Brazilian Chemical Society, 22(6), 1096-1102 (2011)
Zhi Liu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 29(11), 1049-1051 (2005-01-20)
To establish a HPLC method for determining orientin and vitexin in Trollius chinesis preparation. The separation was carried out on Hypersil ODS column with a mixture of acetonitrile-1% acetic acid solution (15:85) as the mobile phase, at a flow rate
X-C Fu et al.
Journal of Asian natural products research, 8(3), 265-272 (2006-07-26)
We investigated the anti-apoptotic effect of orientin, from bamboo leaves (Phyllostachys nigra), on rat heart after treatment with ischemia/reperfusion (I/R), and on rat cardiomyocytes injured by hypoxia/reoxygenation (H/R). I/R injury was induced by occluding the left anterior descending coronary artery
Xiaoqin Li et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 853(1-2), 221-226 (2007-04-10)
A high-performance liquid chromatography (HPLC) method was developed and validated for the determination of orientin in rabbit plasma using ultraviolet (UV) absorbance detection. Orientin is the active constituent of purified herbal extract (TRO PE) from the flower of Trollius chinensis
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