Skip to Content

Key Documents

View All Documentation

56750

Imidazole

≥99.5% (GC), flakes, powder or crystals, puriss. p.a.

Synonym(s):

1,3-Diaza-2,4-cyclopentadiene, Glyoxaline

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
C3H4N2
CAS Number:
288-32-4
Molecular Weight:
68.08
NACRES:
NA.21
PubChem Substance ID:
57651598
eCl@ss:
39161001
UNSPSC Code:
12352005
EC Number:
206-019-2
MDL number:
MFCD00005183
Beilstein/REAXYS Number:
103853
Assay:
≥99.5% (GC)
Form:
flakes, powder or crystals
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Imidazole, puriss. p.a., ≥99.5% (GC)

vapor pressure

<1 mmHg ( 20 °C)

Quality Segment

grade

puriss. p.a.

assay

≥99.5% (GC)

form

flakes, powder or crystals

ign. residue (900 °C)

≤0.1%

pH

9.5-11.0 (25 °C, 50 mg/mL in H2O)

pKa (25 °C)

6.95

bp

256 °C (lit.)

mp

88-91 °C

solubility

alcohol: soluble(lit.), chloroform: soluble(lit.), pyridine: soluble(lit.), water: soluble(lit.)

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

SMILES string

c1c[nH]cn1

InChI

1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)

InChI key

RAXXELZNTBOGNW-UHFFFAOYSA-N

General description

Imidazole is an aromatic heterocyclic compound with a five-membered planar ring. It is an amphoteric compound because of the presence of both an acidic NH and a basic nitrogen atom. Imidazole is an essential component of many important molecules including natural products, bioactive molecules, ionic liquids, and imidazolium. It serves as a building block for the synthesis of various drug molecules.

Application

Excellent for buffers in the range of pH 6.2-7.8
Imidazole can be used as a catalyst:      
  • For the silylation of alcohols, carboxylic acids, and amines in the presence of silyl chloride in DMF.     
  • In the peptide coupling using the triphenyl phosphite.
  • To prepare acid chlorides from the corresponding carboxylic acids and phosgene.

It can also be used in the following reactions:      
  • Imidazole-PPh3/I2 catalytic system used in the conversion of alcohols into iodides      
  • Imidazole-PPh3/I2 is used in the diol deoxygenation reaction.

Other Notes

For titration of aspartic acid and glutamic acid

Still not finding the right product?

Explore all of our products under Imidazole

Signal Word

Danger

Hazard Codes

H302,H314,H360D

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Flash Point (°F)

293.0 °F - closed cup

Flash Point (°C)

145 °C - closed cup

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library