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Merck
CN

59659

Toluidine Red

analytical standard

Synonym(s):

Pigment Red 3

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About This Item

Empirical Formula (Hill Notation):
C17H13N3O3
CAS Number:
2425-85-6
Molecular Weight:
307.30
NACRES:
NA.24
PubChem Substance ID:
329758694
UNSPSC Code:
85151701
EC Number:
219-372-2
MDL number:
MFCD00003910

Key Documents

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InChI key

ZLFVRXUOSPRRKQ-VHEBQXMUSA-N

InChI

1S/C17H13N3O3/c1-11-6-8-14(15(10-11)20(22)23)18-19-17-13-5-3-2-4-12(13)7-9-16(17)21/h2-10,21H,1H3/b19-18+

SMILES string

Cc1ccc(\N=N\c2c(O)ccc3ccccc23)c(c1)[N+]([O-])=O

grade

analytical standard

assay

≥98.0% (HPLC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

270-272 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

Quality Level

100

General description

Toluidine Red is a synthetic organic dye belonging to the class of azo dyes, widely used for restoring or providing color to processed food products.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Toluidine Red may be used as a reference dye for the quantification of the analyte in food products using high-performance liquid chromatography with gel permeation chromatography clean-up procedure.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

CorrosionEnvironment
GHS05,GHS09

signalword

Danger

hcodes

H318,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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Simultaneous determination of fifteen illegal dyes in animal feeds and poultry products by ultra-high-performance liquid chromatography tandem mass spectrometry
Liu R, et al.
Journal of Chromatography A, 879(24), 2416-2422 (2011)
Ying Jiang et al.
Sexually transmitted diseases, 38(3), 244-245 (2010-09-28)
We retrospectively analyzed the Venereal Disease Research Laboratory test, Treponema pallidum particle agglutination test, and toluidine red unheated serum test (TRUST) in 41 cases of HIV-negative neurosyphilis and 34 non-neurologic syphilitic patient and found that serum-TRUST titers could be the
CI Pigment Red 3.
IARC monographs on the evaluation of carcinogenic risks to humans, 57, 259-267 (1993-01-01)
D L Morgan et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 27(12), 793-800 (1989-12-01)
Treatment of F344 rats and B6C3F1 mice with C.I. Pigment Red 3 in the diet (10, 5.0, 2.5, 1.25, 0.6 or 0.3%) for 14 and 90 days resulted in haematological alterations consistent with haemolytic anaemia. Rats appeared to be more
Simultaneous determination of 14 oil-soluble synthetic dyes in chilli products by high performance liquid chromatography with a gel permeation chromatography clean-up procedure
Zhu Y, et al.
Food Chemistry, 145(24), 956-962 (2014)
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