form
powder or crystals
Quality Level
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
impurities
≤0.5% water
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
SMILES string
CCCCc1nc(Cl)c(CO)n1Cc2ccc(cc2)-c3ccccc3-c4nnnn4[K]
InChI
1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
InChI key
OXCMYAYHXIHQOA-UHFFFAOYSA-N
Gene Information
human ... AGTR1(185)
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Related Categories
General description
Application
- Pharmaceutical formulations using reversed-phase high-performance liquid chromatography and UV-spectrophotometric techniques.
- Rat plasma using liquid chromatography–tandem mass spectrometry (LC–MS/MS) technique.
Biochem/physiol Actions
Recommended products
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Example:
Additional examples:
705578-5MG-PW
PL860-CGA/SHF-1EA
MMYOMAG-74K-13
1000309185
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Aldrich Products
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Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
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What is the Department of Transportation shipping information for this product?
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What class of compound is Losartan Potassium, Product 61188?
Losartan is an angiotensin II receptor antagonist that is used to treat hypertension. It has imidazole, tetrazole, and benzene rings as part of its structure. It is anionic at neutral pH; it has a pKa in the range of 4-5.
What HPLC column can I use for the analysis of Losartan in my samples?
Losartan is commonly analyzed using a C18 RP-HPLC column. Here at Supelco, we have successfully separated Valsartan, Losartan, and Irbesartan by HPLC chromatography on an Ascentis Express C18 15cm x 3mm column , using a mobile phase of 45:55, water:(0.1% formic acid in acetonitrile). Run times were less than 3 minutes, with the flow rate set at 0.4 mL/min (35° C).
What do you suggest for sample preparation?
For extraction from biological fluids, consider HybridSPE - precipitation
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