61234
α-Ketoglutaric acid
analytical standard
Synonym(s):
2-Oxoglutaric acid, 2-Oxopentanedioic acid
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Linear Formula:
HOOCCH2CH2COCOOH
CAS Number:
Molecular Weight:
146.10
EC Number:
206-330-3
UNSPSC Code:
41116107
NACRES:
NA.24
Beilstein/REAXYS Number:
1705689
MDL number:
Product Name
α-Ketoglutaric acid, analytical standard
InChI
1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChI key
KPGXRSRHYNQIFN-UHFFFAOYSA-N
SMILES string
OC(=O)CCC(=O)C(O)=O
grade
analytical standard
assay
99.0-101.0% (T)
shelf life
limited shelf life, expiry date on the label
application(s)
clinical testing
format
neat
storage temp.
2-8°C
Looking for similar products? Visit Product Comparison Guide
Related Categories
Application
α-Ketoglutaric acid may be used as an analytical reference standard for the quantification of the analyte in the following:
- Human plasma samples using gas-chromatography coupled to mass spectrometry.
- Beer samples using high-performance liquid chromatography with UV detection, and further confirmed by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS).
- Fruits and vegetables using HPLC-MS/MS.
General description
α-Ketoglutaric acid, an α-ketoacid, is identified as a potential, renal cell carcinoma (RCC) biomarker via urinary metabolomic profiling. It plays an important role in living beings as an angiogenesis suppressor.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Determination of organic acids in fruits and vegetables by liquid chromatography with tandem-mass spectrometry
Flores P, et al.
Food Chemistry, 132(2), 1049-1054 (2012)
Simultaneous quantitative determination of ?-ketoglutaric acid and 5-hydroxymethylfurfural in human plasma by gas chromatography?mass spectrometry
Wagner MB, et al.
Analytical and Bioanalytical Chemistry, 396(7), 2629-2637 (2010)
Simultaneous determination of urinary quinolinate, gentisate, 4-hydroxybenzoate, and ?-ketoglutarate by high-performance liquid chromatography-tandem mass spectrometry
Chen S, et al.
Analytical Methods : Advancing Methods and Applications, 7(16), 6572-6578 (2015)
Single determination of ?-ketoglutaric acid and pyruvic acid in beer by HPLC with UV detection
Montenegro P, et al.
Analytical Methods : Advancing Methods and Applications, 3(5), 1207-1212 (2011)
Gas chromatographic profiling and pattern recognition analysis of urinary organic acids from uterine myoma patients and cervical cancer patients
Kim R-K, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 712(1-2), 11-22 (1998)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service