63406
Methyl malonyl chloride
purum, ≥97.0% (AT)
Synonym(s):
Methyl chloroformylacetate
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
CH3OCOCH2COCl
CAS Number:
Molecular Weight:
136.53
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
253-540-6
Beilstein/REAXYS Number:
1754078
MDL number:
Assay:
≥97.0% (AT)
grade
purum
Quality Level
assay
≥97.0% (AT)
refractive index
n20/D 1.432
bp
57-59 °C/12 mmHg (lit.)
density
1.273 g/mL at 25 °C (lit.)
functional group
acyl chloride, ester
storage temp.
2-8°C
SMILES string
COC(=O)CC(Cl)=O
InChI
1S/C4H5ClO3/c1-8-4(7)2-3(5)6/h2H2,1H3
InChI key
UTBCRHAMJFMIIR-UHFFFAOYSA-N
Application
Methyl malonyl chloride can be used in the synthesis of methyl 7-hydroxy[1,3]thiazolo[5,4-b]pyridin-5(4H)-one-6-carboxylates and 6-carboxamides, which can act like HIV integrase strand transfer inhibitors. It can also be used in the synthesis of Strychnos alkaloids like (-)-leuconicine A and (-)-leuconicine B.
Disclaimer
may discolor to yellow on storage
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
176.0 °F - closed cup
flash_point_c
80 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Protocols
Photometric determination with Cuprizon subsequent to acid mineralisation
酸矿化后使用 Cuprizon 进行光度测定
"Synthesis and HIV-integrase strand transfer inhibition activity of 7-hydroxy [1, 3] thiazolo [5, 4-b]pyridin-5 (4H)-ones"
Boros.EE, et al.
Bioorganic & Medicinal Chemistry, 16(21), 5668-5672 (2006)
"Total synthesis of (-)-leuconicine A and B"
Sirasani G and Andrade.BR
Organic Letters, 13(17), 4736-4737 (2011)
Elif Okutan et al.
Journal of fluorescence, 26(6), 2333-2343 (2016-11-01)
Colorimetric fluorescent chemosensors 4 and 5 based on mono- and di- styryl borondipyrromethenes (BODIPY) linked methyl malonyl were designed for detection of hemoglobin (HgB). Their sensing behavior toward various analytes (Br
Global Trade Item Number
| SKU | GTIN |
|---|---|
| Y0000576-0.8MG | 04061832621449 |
| Y0000576 | 04061833795804 |
| L1764-50MG | 04061833949559 |
| BP434 | 04061834337331 |
| 1370305-200MG | 04061833020227 |
| L0750500 | 04061833836644 |
| PHR8985-500MG | 04065268554807 |
| 63406-10ML | 04061836693015 |
| 63406-50ML | 04061836699727 |