67403
Cirsilineol
analytical standard
Synonym(s):
4′,5-Dihydroxy-3′,6,7-trimethoxyflavone, 6-Methoxyluteolin 3′,7-dimethyl ether, Anisomelin, Eupatrin, Fastigenin
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About This Item
Empirical Formula (Hill Notation):
C18H16O7
CAS Number:
Molecular Weight:
344.32
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1355108
grade
analytical standard
Quality Level
assay
≥95.0% (HPLC and enzymatic)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
SMILES string
COc1cc(ccc1O)C2=CC(=O)c3c(O)c(OC)c(OC)cc3O2
InChI
1S/C18H16O7/c1-22-13-6-9(4-5-10(13)19)12-7-11(20)16-14(25-12)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3
InChI key
VKOSQMWSWLZQPA-UHFFFAOYSA-N
General description
Cirsilineol is a bioactive flavone isolated from the herb of Artemisia vestita Wall., widely used to treat a variety of inflammatory conditions such as contact dermatitis, rheumatoid arthritis and sepsis. Cirsilineol exhibits anti-proliferative activity, which is used against different cancer cells by inducing apoptosis.
Application
Cirsilineol may be used as an analytical reference standard for the quantification of the analyte in vervain samples and extracts of Teucrium polium using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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[Flavones isolated from Thymus carnosus Boiss].
E Maruhenda et al.
Annales pharmaceutiques francaises, 45(6), 467-470 (1987-01-01)
Xia Sheng et al.
The Journal of pharmacy and pharmacology, 60(11), 1523-1529 (2008-10-30)
Cirsilineol (4',5-dihydroxy-3',6,7-trimethoxyflavone) is a compound isolated from the herb of Artemisia vestita Wall (Compositae). In this study, we aimed at examining the anti-proliferative activity of cirsilineol against multiple types of cancer cells and the underlying mechanisms. Cirsilineol significantly inhibited proliferation
Qi-wei Zhang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 27(1), 23-25 (2003-05-31)
To establish a quantitative method for determination of cirsilineol in Herba Artemisiae Scopariae collected in Autumn. Sample was extracted with methanol, and cleaned up with polyamide column. ODS column was used with methanol-acetonitrile-0.5% acetic acid solution (24:19:57) as mobile phase.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 67403-5MG | 04061833238486 |