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Merck
CN

680303

Tetrahydrofuran solution

contains 20 % (v/v) 1,2-Propanediol

Synonym(s):

Butylene oxide, Oxolane, THF, Tetramethylene oxide

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About This Item

CAS Number:
UNSPSC Code:
12352005
PubChem Substance ID:
MDL number:
Technical Service
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form

liquid

Quality Level

contains

20 % (v/v) 1,2-Propanediol

impurities

≤0.20% water, 0.02 meq/g Titr. acid, 0.02 meq/g Titr. base

color

APHA: 1

density

0.914 g/mL at 25 °C

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

General description

The product is a tetrahydrofuran (THF) solution containing 20%(v/v) 1,2-propanediol. THF, a saturated cyclic ester, is a water miscible organic solvent. The combustion studies of THF have been reported.
Tetrahydrofuran (THF) solution is THF in 20% (v/v) 1,2-propanediol. THF a saturated cyclic ester, is a water-miscible organic solvent. THF has been a widely used industrial solvent for varnishes and PVC (polyvinyl chloride), polymerization, electrochemistry, and pharmaceutical.

Application


  • Self-Assembly of Polyoxometalate-Based Nanoparticle Surfactants in Solutions: Highlights the use of Tetrahydrofuran as a critical solvent in the synthesis and self-assembly of polyoxometalate-based nanoparticles, exploring applications that could impact multiple fields including polymer research, drug delivery systems, and nanostructured materials (Xia et al., 2024).

  • Highly sensitive fluorescence turn-OFF and reversible chemical sensor for Hg(2+) ion based on pyrene appended 2-thiohydantoin: Tetrahydrofuran is used as a key solvent in the development of a novel fluorescence-based chemical sensor for mercury detection, demonstrating its application in environmental monitoring and safety in laboratory settings (Gawas et al., 2024).

  • Effect of Plasma pretreatment and Graphene oxide ratios on the transport properties of PVA/PVP membranes for fuel cells: This research employs Tetrahydrofuran as a processing solvent in the creation of polyvinyl alcohol/polyvinylpyrrolidone membranes enhanced with graphene oxide, focusing on improvements in ion transport for fuel cell applications (Abdel-Hamed et al., 2024).

  • Optimized Incorporation of Furan into Diketopyrrolopyrrole-Based Conjugated Polymers for Organic Field-Effect Transistors: Utilizes Tetrahydrofuran as a solvent to aid in the synthesis of novel conjugated polymers, potentially leading to advancements in organic electronics and polymer research (Neu et al., 2024).



signalword

Danger

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Respiratory system

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

-6.2 °F - (THF)

flash_point_c

-21.2 °C - (THF)

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Highly selective hydrolytic kinetic resolution of terminal epoxides catalyzed by chiral (salen) CoIII complexes. Practical synthesis of enantioenriched terminal epoxides and 1,2-diols.
Schaus SE, et al.
Journal of the American Chemical Society, 124(7), 1307-1315 (2002)
An experimental and modeling study of the combustion of tetrahydrofuran.
Tran LS, et al.
Combustion and Flame, 162(5), 1899-1918 (2015)
Ilaria Massarelli et al.
European journal of medicinal chemistry, 44(9), 3658-3664 (2009-03-11)
A dataset comprising 55 chemicals with hepatocarcinogenic potency indices was collected from the Carcinogenic Potency Database with the aim of developing QSAR models enabling prediction of the above unwanted property for New Chemical Entities. The dataset was rationally split into



Global Trade Item Number

SKUGTIN
680303-4X4L04061832750927