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68300

Tazobactam sodium salt

analytical standard

Synonym(s):

CL-298741, YTR-830H, [2S-(2α, 3β, 5α)]-3-Methyl-7-oxo-3(1H,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide

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About This Item

Empirical Formula (Hill Notation):
C10H11N4NaO5S
CAS Number:
89785-84-2
Molecular Weight:
322.27
NACRES:
NA.24
PubChem Substance ID:
329760787
UNSPSC Code:
41116107
MDL number:
MFCD00917472
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grade

analytical standard

Quality Level

100

assay

≥98.0% (HPLC)

optical activity

[α]/D 144±4°, c = 0.1 in H2O

shelf life

limited shelf life, expiry date on the label

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na+].C[C@]2(Cn1ccnn1)[C@@H](N3[C@@H](CC3=O)S2(=O)=O)C([O-])=O

InChI

1S/C10H12N4O5S.Na/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19;/h2-3,7-8H,4-5H2,1H3,(H,16,17);/q;+1/p-1/t7-,8+,10+;/m1./s1

InChI key

RFMIKMMOLPNEDG-QVUDESDKSA-M

General description

Tazobactam sodium is the sodium salt of the β-lactamase inhibitor antibiotic, tazobactam. It is a semisynthetic parenteral penicillin which can be combined with piperacillin and ceftolozane drugs for treating a variety of infections.

Application

Tazobactam sodium may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by reversed-phase high-performance liquid chromatography.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN4035
BCCM1511
BCCL1894
BCCJ3392
BCCH6530

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RP-HPLC method for simultaneous estimation of cefepime hydrochloride and tazobactam sodium in bulk and pharmaceuticals
Tamboli SR and Patil DD
Journal of Chemistry, 2013(1), 127-131 (2013)
Stability indicating RP-HPLC method for the estimation of ceftazidime pentahydrate and tazobactam sodium in bulk and dosage forms
Amareswari S, et al.
Indian Journal of Pharmaceutical and Biological Research, 1(4), 543-543 (2013)
RP-HPLC method for simultaneous estimation of cefepime hydrochloride and tazobactam sodium in bulk and pharmaceuticals
Tamboli SR and Patil DD
Journal of Chemistry, 2013(4), 543-543 (2013)
View All Related Papers

Global Trade Item Number

SKUGTIN
68300-10MG04061832755243
68300-5MG04061832755267