Skip to Content
Merck
CN

69480

N-Methyl-N-trimethylsilylacetamide

derivatization grade (GC derivatization), LiChropur™, ≥97.0% (GC)

Synonym(s):

MSA

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C6H15NOSi
CAS Number:
7449-74-3
Molecular Weight:
145.27
UNSPSC Code:
23151816
NACRES:
NA.22
PubChem Substance ID:
329761691
EC Number:
231-217-0
Beilstein/REAXYS Number:
506975
MDL number:
MFCD00040758

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

N-Methyl-N-trimethylsilylacetamide, derivatization grade (GC derivatization), LiChropur™, ≥97.0% (GC)

InChI key

QHUOBLDKFGCVCG-UHFFFAOYSA-N

InChI

1S/C6H15NOSi/c1-6(8)7(2)9(3,4)5/h1-5H3

SMILES string

CN(C(C)=O)[Si](C)(C)C

grade

derivatization grade (GC derivatization)

assay

≥97.0% (GC)

form

liquid

quality

LiChropur™

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.439

bp

159-161 °C (lit.)

density

0.904 g/mL at 20 °C (lit.)

storage temp.

−20°C

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

Application

N-Methyl-N-trimethylsilylacetamide may be used as a derivatizing reagent for the following:       
  • Quantification of the carbohydrate intermediates in glycation systems using gas chromatography coupled to mass spectrometry technique.       
  • Characterization of damaged products of thymine and cytosine formed by the exposure to UV light in a hydrogen peroxide solution using gas chromatography/mass spectrometry with scan mode and selected ion monitoring mode.

General description

N-Methyl-N-trimethylsilylacetamide is a trialkyl-silyl reagent and a versatile derivatizing agent used in gas chromatography (GC).

Other Notes

Powerful silylating agent for polar compounds

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

Flame
GHS02

signalword

Warning

hcodes

H226

Hazard Classifications

Flam. Liq. 3

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

118.4 °F - closed cup

flash_point_c

48.0 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCB7757

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hua-Hao Zhang et al.
Mobile DNA, 9, 19-19 (2018-06-28)
Transposable elements (TEs) are common and often present with high copy numbers in cellular genomes. Unlike in cellular organisms, TEs were previously thought to be either rare or absent in viruses. Almost all reported TEs display only one or two
Ahmad Alabdulkareem et al.
Science advances, 4(7), eaao6030-eaao6030 (2018-07-24)
Economic inequality is one of the biggest challenges facing society today. Inequality has been recently exacerbated by growth in high- and low-wage occupations at the expense of middle-wage occupations, leading to a "hollowing" of the middle class. Yet, our understanding
Fermín Segovia et al.
Frontiers in neuroinformatics, 11, 23-23 (2017-04-21)
An early and differential diagnosis of parkinsonian syndromes still remains a challenge mainly due to the similarity of their symptoms during the onset of the disease. Recently
Shu-Jun Wei et al.
Ecology and evolution, 7(14), 5400-5409 (2017-08-05)
Genetic comparisons of parasitoids and their hosts are expected to reflect ecological and evolutionary processes that influence the interactions between species. The parasitoid wasp
Cameron J Hunt et al.
Scientific reports, 7(1), 17315-17315 (2017-12-13)
Ferulic acid esterases (FAE, EC 3.1.1.73) cleave the arabinose hydroxycinnamate ester in plant hemicellulose and other related substrates. FAE are commonly categorised as type A-D based on catalytic activities towards model, short alkyl chain esters of hydroxycinnamates. However, this system
View All Related Papers

Articles

Silylation of Non-Steroidal Anti-Inflammatory Drugs

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service