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N-Methyl-N-trimethylsilylacetamide

derivatization grade (GC derivatization), LiChropur, ≥97.0% (GC)

Synonym(s):

MSA

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About This Item

Empirical Formula (Hill Notation):
C6H15NOSi
CAS Number:
Molecular Weight:
145.27
Beilstein:
506975
EC Number:
MDL number:
UNSPSC Code:
23151816
PubChem Substance ID:
NACRES:
NA.22

grade

derivatization grade (GC derivatization)

Quality Level

Assay

≥97.0% (GC)

form

liquid

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.439

bp

159-161 °C (lit.)

density

0.904 g/mL at 20 °C (lit.)

storage temp.

−20°C

SMILES string

CN(C(C)=O)[Si](C)(C)C

InChI

1S/C6H15NOSi/c1-6(8)7(2)9(3,4)5/h1-5H3

InChI key

QHUOBLDKFGCVCG-UHFFFAOYSA-N

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General description

N-Methyl-N-trimethylsilylacetamide is a trialkyl-silyl reagent and a versatile derivatizing agent used in gas chromatography (GC).

Application

N-Methyl-N-trimethylsilylacetamide may be used as a derivatizing reagent for the following:       
  • Quantification of the carbohydrate intermediates in glycation systems using gas chromatography coupled to mass spectrometry technique.       
  • Characterization of damaged products of thymine and cytosine formed by the exposure to UV light in a hydrogen peroxide solution using gas chromatography/mass spectrometry with scan mode and selected ion monitoring mode.

Other Notes

Powerful silylating agent for polar compounds

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Flame

Signal Word

Warning

Hazard Statements

Hazard Classifications

Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

118.4 °F - closed cup

Flash Point(C)

48.0 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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