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Merck
CN

70382

Sodium 1,2-naphthoquinone-4-sulfonate

for spectrophotometric det. of isonicotic hydrazide, amines and amino acids, ≥97.0% (T)

Synonym(s):

1,2-Naphthoquinone-4-sulfonic acid sodium salt, 3,4-Dihydro-3,4-dioxo-1-naphthalenesulfonic acid sodium salt, Folin’s reagent

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About This Item

Empirical Formula (Hill Notation):
C10H5NaO5S
CAS Number:
Molecular Weight:
260.20
Beilstein/REAXYS Number:
4169788
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21
PubChem Substance ID:
EC Number:
208-308-9
Assay:
≥97.0% (HPLC), ≥97.0% (T)
Form:
powder
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InChI

1S/C10H6O5S.Na/c11-8-5-9(16(13,14)15)6-3-1-2-4-7(6)10(8)12;/h1-5H,(H,13,14,15);/q;+1/p-1

InChI key

UBLXEEBHYISRFM-UHFFFAOYSA-M

SMILES string

[Na+].[O-]S(=O)(=O)C1=CC(=O)C(=O)c2ccccc12

assay

≥97.0% (HPLC), ≥97.0% (T)

form

powder

quality

for spectrophotometric det. of isonicotic hydrazide, amines and amino acids

specific analyte(s)

sodium

technique(s)

UV/Vis spectroscopy: suitable, photometry: suitable

solubility

H2O: 50 mg/mL, clear

Other Notes

Determination of amines

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Y. Asahi et al.
Chemical & Pharmaceutical Bulletin, 32, 3093-3093 (1984)
C. Molins Legua et al.
Fresenius Journal of Analytical Chemistry, 349, 311-311 (1994)
P Nagaraja et al.
Journal of pharmaceutical and biomedical analysis, 17(3), 501-506 (1998-07-10)
A rapid, sensitive and simple spectrophotometric method is proposed for the determination of hydrolysis products of paracetamol (PRL) and phenacetin (PHN) with sodium 1,2-naphthoquinone-4-sulphonate and cetyltrimethyl ammonium bromide (CTA) in alkaline medium. The absorbances are measured at 570 and 500
Masoumeh Hasani et al.
Analytical biochemistry, 365(1), 74-81 (2007-03-22)
A spectrophotometric method for simultaneous analysis of glycine and lysine is proposed by application of neural networks on the spectral kinetic data. The method is based on the reaction of glycine and lysine with 1,2-naphthoquinone-4-sulfonate (NQS) in slightly basic medium.
Li Xiao Xu et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 59(13), 3103-3110 (2003-10-30)
Spectrophotometric determination of procaine hydrochloride is described. The procaine hydrochloride reacts with 1,2-naphthoquinone-4-sulfonic acid in pH 3.60 buffer solution to form a salmon pink compound, and its maximum absorption wavelength is at 484 nm, epsilon(484)=5.22 x 10(3).The absorbance for procaine

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