73436
Indigo carmine
analytical standard
Synonym(s):
Acid Blue 74, Indigo-5,5′-disulfonic acid disodium salt, Indigocarmine
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About This Item
Empirical Formula (Hill Notation):
C16H8N2Na2O8S2
CAS Number:
Molecular Weight:
466.35
UNSPSC Code:
85151701
NACRES:
NA.24
E Number:
E132
PubChem Substance ID:
EC Number:
212-728-8
MDL number:
Colour Index Number:
73015
Beilstein/REAXYS Number:
4103904
Product Name
Indigo carmine, analytical standard
InChI
1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2/b14-13+;;
SMILES string
[Na+].[Na+].[O-]S(=O)(=O)c1ccc2NC(\C(=O)c2c1)=C3\Nc4ccc(cc4C3=O)S([O-])(=O)=O
InChI key
KHLVKKOJDHCJMG-QDBORUFSSA-L
grade
analytical standard
assay
≥97.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
cleaning products
cosmetics
food and beverages
personal care
format
neat
Quality Level
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Application
Indigo carmine may be used as a test material to investigate its interaction with the calf thymus DNA in physiological buffer (pH 7.4) with the use of ethidium bromide (EB) dye as a fluorescence probe by spectroscopic studies. It may be used as an analytical reagent for spectrophotometric determination of pantoprazole sodium sesquihydrate (PNT) in pure form and dosage forms using a bromide-bromide mixture. IC may also be used as an analytical reference standard for the quantification of the analyte in food products using microemulsion electrokinetic chromatography (MEEKC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Indigo carmine (IC), a synthetic indigoid dye, belongs to the class of food dyes used to impart colorless foodstuffs a more characteristic appearance as well as to change the original color, texture of the food products and maintain natural color during processing and storage of food products.
This product is provided by Sigma-Aldrich, as a neat standard for the precise quality control of food products. In the European Union, E numbers are used as codes for food color additives. E numbers 100-199 include not only artificial food colors derived from petroleum, but also natural additives originating from sources such as vegetables, insects or mixtures made from natural foodstuffs. IC is widely used in a variety of food products including fruit juices, bread, smoked fish, sweets, tomatoes, catsup, dairy, skim milk products, etc.
This product is provided by Sigma-Aldrich, as a neat standard for the precise quality control of food products. In the European Union, E numbers are used as codes for food color additives. E numbers 100-199 include not only artificial food colors derived from petroleum, but also natural additives originating from sources such as vegetables, insects or mixtures made from natural foodstuffs. IC is widely used in a variety of food products including fruit juices, bread, smoked fish, sweets, tomatoes, catsup, dairy, skim milk products, etc.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 1
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Sensitive spectrophotometric methods for the determination of pantoprazole sodium in pharmaceuticals using bromate-bromide, methyl orange and indigo carmine as reagents
Basavaiah K and Kumar ARU
Indian Journal of Chemical Technology, 14, 611-615 (2007)
Spectroscopic studies of DNA interactions with food colorant indigo carmine with the use of ethidium bromide as a fluorescence probe
Ma Y, et al.
Journal of Agricultural and Food Chemistry, 60(43), 10867-10875 (2012)
Determination of food colorants by microemulsion electrokinetic chromatography
Huang Y-H, et al.
Electrophoresis, 26(4-5), 867-877 (2005)
Tsuneo Oyama
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 25 Suppl 1, 7-12 (2013-03-27)
The indication of endoscopic submucosal dissection for Barrett's esophageal adenocarcinoma (BEA) is superficial BEA without lymph node metastasis. The characteristic endoscopic findings of superficial BEA are elevation, depression, and color change. Indigocarmine spreading is useful for the diagnosis of lateral
Christian Gómez-Solís et al.
Journal of hazardous materials, 217-218, 194-199 (2012-04-03)
Indigo carmine and methylene blue dyes in aqueous solution were photodegraded using SiC-TiO(2) catalysts prepared by sol-gel method. After thermal treatment at 450°C, SiC-TiO(2) catalysts prepared in this work showed the presence of SiC and TiO(2) anatase phase. Those compounds
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