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73569

2-Methyl-4-isothiazolin-3-one

analytical standard

Synonym(s):

2-Methyl-3(2H)-isothiazolone

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About This Item

Empirical Formula (Hill Notation):
C4H5NOS
CAS Number:
2682-20-4
Molecular Weight:
115.15
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329765047
EC Number:
220-239-6
Beilstein/REAXYS Number:
606203
MDL number:
MFCD01742315
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grade

analytical standard

Quality Level

100

assay

≥98.0% (GCF)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤13.0% water (Karl Fischer)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

CN1SC=CC1=O

InChI

1S/C4H5NOS/c1-5-4(6)2-3-7-5/h2-3H,1H3

InChI key

BEGLCMHJXHIJLR-UHFFFAOYSA-N

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General description

This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Application

2-Methyl-4-isothiazolin-3-one may be used as an antimicrobial preservative for the analysis of Ochratoxin A in spices using clean-up tandem immunoassay columns followed by confirmation by high performance liquid chromatography technique and in non-formalin products for wallpaper adhesives using gas chromatography technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1A

supp_hazards

EUH071

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM7231
BCCM1860
BCCM6011
BCCM5286
BCCL6427

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Determination of antimicrobial agents in non-formalin adhesives for wallpaper
Nakashima H, et al.
Journal of Health Science, 46(6), 447-454 (2000)
Effects of a mixture of chloromethylisothiazolinone and methylisothiazolinone on peripheral airway dysfunction in children
Cho J-H, et al.
PLoS ONE, 2(4) (2017)
Approach for ochratoxin A fast screening in spices using clean-up tandem immunoassay columns with confirmation by high performance liquid chromatography?tandem mass spectrometry (HPLC?MS/MS)
Goryacheva.Y.I, et al.
Analytica Chimica Acta, 577(1), 38-45 (2006)
Simultaneous Determination of Ultraviolet Absorbers and Antibacterial Agents in Textiles by Ultra-High Performance Liquid Chromatography/Orbitrap High Resolution Mass Spectrometry
Wang C, et al.
World Journal of Engineering and Technology, 5(01), 1-1 (2017)
Julien Mutschler et al.
Toxicology in vitro : an international journal published in association with BIBRA, 23(3), 439-446 (2009-05-16)
Assessment of skin sensitization hazard of chemicals currently depends on in vivo methods. Considering the forthcoming European Union ban on in vivo testing of cosmetic/toiletry ingredients, the search for alternative non-animal approaches is an urgent challenge for investigators today. For
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Global Trade Item Number

SKUGTIN
73569-1G04061832875057

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