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Merck
CN

74460

(−)-Norepinephrine

≥98.0% (sum of enantiomers, HPLC)

Synonym(s):

(R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol, L-Arterenol, L-Noradrenaline, Levarterenol

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About This Item

Empirical Formula (Hill Notation):
C8H11NO3
CAS Number:
51-41-2
Molecular Weight:
169.18
EC Number:
200-096-6
UNSPSC Code:
12352200
MDL number:
MFCD00025592
Beilstein/REAXYS Number:
2804840

Key Documents

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assay

≥98.0% (sum of enantiomers, HPLC)

optical activity

[α]20/D −45±3°, c = 5% in 1 M HCl

storage temp.

2-8°C

SMILES string

NC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1

InChI key

SFLSHLFXELFNJZ-QMMMGPOBSA-N

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Jacques Albanèse et al.
Chest, 126(2), 534-539 (2004-08-11)
To assess the effects of a norepinephrine-induced vasoconstriction on renal function in septic and nonseptic patients. Open-label prospective study. Medical-surgical ICU in an urban teaching hospital. Fourteen patients with septic shock and 12 uninfected patients with head trauma (Glasgow coma
Terry McMorris et al.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 61(2), 204-215 (2005-11-29)
The primary aims of this paper were to examine the effect of heat stress on working memory, choice reaction time and mood state, and to investigate the relationship between heat induced changes in plasma concentrations of selected neurotransmitters and hormones
Junji Shibahara et al.
The American journal of surgical pathology, 28(6), 825-829 (2004-05-29)
We describe a case of primary pulmonary paraganglioma, a tumor that has not been reported in sufficient detail in previous literature. The patient was a 55-year-old woman with hypertension accompanied by an elevated serum norepinephrine level (2651 pg/mL; normal 100-450
C R Lake et al.
Science (New York, N.Y.), 207(4428), 331-333 (1980-01-18)
Concentrations of norepinephrine in cerebrospinal fluid are higher in schizophrenic patients, particularly in those with paranoid features, than in normal volunteer subjects of the same age. This observation supports recent reports of elevated concentrations of norepinephrine in specific brain areas
H Alec Ross et al.
The Journal of pharmacology and experimental therapeutics, 319(2), 840-846 (2006-08-12)
Microdialysis is a sampling method that permits measurement of hormones, drugs, and other lower molecular weight compounds present in interstitial fluid. We developed a straightforward mathematical model that predicts a linear relationship between the reciprocal dialysate concentration of the analyte
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