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75423

Vancomycin supplement

Name: Vancomycin supplement
Brand: SIAL

for Enterobacter spp., powder, pack of 5 vials, suitable for microbiology

Synonym(s):

Vancomycin hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₆₆H₇₅Cl₂N₉O₂₄ · xHCl

CAS Number:

1404-93-9

Molecular Weight:

1449.25 (free base basis)

MDL number:

MFCD00064593

UNSPSC Code:

41171614

NACRES:

NA.85

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Properties

Quality Segment

200

agency

according to GB 4789.40-2016, according to ISO 22964:2017

sterility

sterile

form

powder

shelf life

limited shelf life, expiry date on the label

packaging

pack of 5 vials

color

white

application(s)

environmental
food and beverages, microbiology

storage temp.

2-8°C

suitability

Enterobacter spp.

SMILES string

[Cl-].Clc1c2ccc(c1)[C@H]([C@@H]3NC(=O)[C@H](NC(=O)[C@@H]6NC(=O)[C@@H](NC(=O)[C@@H]([C@@H](c7cc(c(cc7)Oc8c(c(cc6c8)O2)O[C@@H]9O[C@@H]([C@H]([C@@H]([C@H]9O[C@@H]%10O[C@H]([C@H]([C@](C%10)(N)C)O)C)O)O)CO)Cl)O)NC(=O)[C@H]([N+H2]C)CC(C)C)CC(=O)N)c4cc(c(cc4)O)c

InChI

1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1

InChI key

LCTORFDMHNKUSG-XTTLPDOESA-N

Description

General description

Vancomycin supplement is a microbiology-grade antibiotic supplement used torender culture media selective for certain Gram‑negative bacteria. It consists of vancomycin hydrochloride, a glycopeptideantibiotic with strong activity against Gram‑positive organisms but little activity against Gram‑negative bacteria. The supplement is intended to be added to appropriatebase media to inhibit accompanying Gram‑positive flora and thereby improve recovery and selective enrichment oftarget Gram‑negative species such asEnterobacter sakazakii (now Cronobacter spp.). ISO methodsrecommend this supplement for the selective enrichment of Enterobactersakazakii in food and environmental samples.

Application

Vancomycin supplement is primarily used as an antibiotic additive forselective enrichment media, especially in methods aligned with ISOrecommendations to detect Enterobacter sakazakii/Cronobacterspp. in powdered infant formula and related products. It has also been employedin selective media to investigate vancomycin‑resistant enterococci (VRE) in treated wastewater and other environmentalsamples, where defined concentrations of vancomycin are used to select forresistant populations while suppressing susceptible Gram‑positive bacteria

Other Notes

(per vial, sufficient for 1000 ml medium)
Vancomycin 10.00 mg

pictograms

GHS08

signalword

Danger

hcodes

H317,H334

pcodes

P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c