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Tryptamine

analytical standard

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Synonym(s):
2-(3-Indolyl)ethylamine, 3-(2-Aminoethyl)indole
Empirical Formula (Hill Notation):
C10H12N2
CAS Number:
61-54-1
Molecular Weight:
160.22
Beilstein:
125513
EC Number:
200-510-5
MDL number:
MFCD00005661
PubChem Substance ID:
329767281
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥97.5% (GC)
97.5-102.5% (NT)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

137 °C/0.15 mmHg (lit.)

mp

113-116 °C (lit.)

suitability

conforms to structure for Infrared spectrum

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

NCCc1c[nH]c2ccccc12

InChI

1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2

InChI key

APJYDQYYACXCRM-UHFFFAOYSA-N

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General description

Tryptamines which are usually found in plants, fungi, animals, etc. are categorized under the monoamine alkaloids class of compounds.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tryptamine has been used as a reference standard for the determination of tryptamine in fish and fish products by liquid chromatography (LC) combined with single-stage Orbitrap high resolution mass spectrometry (HRMS), in Polish wine samples by direct solid phase microextraction coupled to gas chromatography-mass spectrometry (DI-SPME-GC-MS), in Korean turbid rice wine, Makgeolli by ultra-high-pressure liquid chromatography-electrospray tandem mass spectrometry (UHPLC-ESI-MS/MS) and in beer by a non-woven nanofibre mat in combination with solid surface-room temperature phosphorescence (SS-RTP).

Biochem/physiol Actions

Vasoactive; may have a neuromodulator function; biogenic amine formed from the decarboxylation of tryptophan by L-aromatic amino acid decarboxylase.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302 - H317 - H318

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1A

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

365.0 °F

Flash Point(C)

185 °C

Certificates of Analysis (COA)

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705578-5MG-PW

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Recreational use, analysis and toxicity of tryptamines.
Tittarelli R, et al.
Current Neuropharmacology, 13(1), 26-46 (2015)
The identification and quantification of biogenic amines in Korean turbid rice wine, Makgeolli by HPLC with mass spectrometry detection.
Lee S, et al.
LWT--Food Science and Technology, 62(1), 350-356 (2015)
Easy and Fast Method for the Determination of Biogenic Amines in Fish and Fish Products with Liquid Chromatography Coupled to Orbitrap Tandem Mass Spectrometry.
Kaufmann A and Maden K
Journal of AOAC (Association of Official Analytical Chemists) International, 101(2), 336-341 (2018)
Novel optical sensing film based on a functional nonwoven nanofibre mat for an easy, fast and highly selective and sensitive detection of tryptamine in beer.
Ramon-Marquez T, et al.
Biosensors And Bioelectronics, 79(1), 600-607 (2016)
Direct solid phase microextraction combined with gas chromatography-Mass spectrometry for the determination of biogenic amines in wine.
Papageorgiou M, et al.
Talanta, 183(2), 276-282 (2018)
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