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Merck
CN

79109

2-Ethoxyethanol

analytical standard

Synonym(s):

Ethyl glycol, Ethylene glycol monoethyl ether

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About This Item

Linear Formula:
C2H5OCH2CH2OH
CAS Number:
110-80-5
Molecular Weight:
90.12
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329768258
EC Number:
203-804-1
Beilstein/REAXYS Number:
1098271
MDL number:
MFCD00002869

Key Documents

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Product Name

2-Ethoxyethanol, analytical standard

InChI key

ZNQVEEAIQZEUHB-UHFFFAOYSA-N

InChI

1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3

SMILES string

CCOCCO

grade

analytical standard

vapor density

3.1 (vs air)

vapor pressure

3.8 mmHg ( 20 °C)

assay

≥99.8% (GC)

autoignition temp.

460 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

14 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.407 (lit.)
n20/D 1.408

bp

135 °C (lit.)

mp

−90 °C (lit.)

density

0.93 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

Quality Level

100

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Application

2-Ethoxyethanol may be used as an extraction solvent for the quantification and analysis of algal lipids from algae samples using normal-phase high performance liquid chromatography(HPLC) coupled in parallel to an evaporative light scattering detector (ELSD) and quadrupole mass spectrometer(QMS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

2-Ethoxyethanol is an organic compound, widely used as a component or solvent for nitrocellulose and in a variety of dyes, inks, cleaning agents, resins, paints, varnishes, etc. It is also used for increasing the stability of emulsions.
This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

104.0 °F - closed cup

flash_point_c

40 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCK4192
BCCF5998
BCCF4814
BCCC5554
BCBW0910

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Extraction of algal lipids and their analysis by HPLC and mass spectrometry
Jones J, et al.
Journal of the American Oil Chemists' Society, 89(8), 1371-1381 (2012)
Rui-Sheng Wang et al.
Industrial health, 45(4), 574-578 (2007-09-20)
Ethylene glycol monoethyl ether (EGEE) can cause damage to testes and sperm, and its metabolites are believed to play an important role in its toxicity. Aldehyde dehydrogenase 2 (ALDH2) is involved in the metabolism of this chemical. To investigate whether
Douglas J Fort et al.
Drug and chemical toxicology, 25(3), 293-308 (2002-08-14)
Currently, no standardized and well-validated alternative models exist for screening for progesterone-responsive endocrine disrupting chemicals (EDCs). Because of this, a rapid assay for evaluating progestin/antiprogestin activity using Xenopus oocyte germinal vesicle breakdown (GVBD) as a model was evaluated. Five compounds
I A Adedara et al.
Andrologia, 45(2), 111-119 (2012-06-20)
Endocrine disrupting chemicals cause reproductive dysfunction by interacting with intricate regulation and cellular processes involve in spermatogenesis. This study investigated the probable mechanism of action of ethylene glycol monoethyl ether (EGEE) as an antiandrogenic compound as well as the effects
David J Lockley et al.
Toxicology and applied pharmacology, 180(2), 74-82 (2002-04-24)
Percutaneous absorption and cutaneous metabolism of 2-ethoxyethanol were assessed in vivo and with an in vitro flow-through diffusion system. Topical application of undiluted (14)C-ethoxyethanol to occluded rat skin in vivo resulted in 25% of the dose being absorbed after 24
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