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Merck
CN

80073

α-Hydroxymetoprolol

analytical standard

Synonym(s):

3-[4-(1-Hydroxy-2-methoxyethyl)phenoxy]-1-isopropylamino-2-propanol, 4-{2-Hydroxy-3-[(1-methylethyl)amino]propoxy}-α-(methoxymethyl)-benzenemethanol

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About This Item

Empirical Formula (Hill Notation):
C15H25NO4
CAS Number:
Molecular Weight:
283.36
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6571082
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grade

analytical standard

Quality Level

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

68-74 °C

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

OC(CNC(C)C)COC1=CC=C(C(O)COC)C=C1

InChI

1S/C15H25NO4/c1-11(2)16-8-13(17)9-20-14-6-4-12(5-7-14)15(18)10-19-3/h4-7,11,13,15-18H,8-10H2,1-3H3

InChI key

OFRYBPCSEMMZHR-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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B Everts et al.
European journal of clinical pharmacology, 53(1), 23-31 (1997-01-01)
Pain intensity and the plasma concentrations of metoprolol and its major metabolite alpha-hydroxymetoprolol as well as noradrenaline (NA), adrenaline (A) and neuropeptide Y (NPY) were determined in patients with pain due to definite or suspected acute myocardial infarction (AMI) after
Paula Macedo Cerqueira et al.
Chirality, 15(6), 542-549 (2003-05-30)
Direct stereoselective separation on chiral stationary phase was developed for HPLC analysis of the four stereoisomers of alpha-hydroxymetoprolol in human plasma and urine. Plasma samples were prepared using solid-phase extraction columns and urine samples were prepared by liquid-liquid extraction. The
Vanessa Bergamin Boralli et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 823(2), 195-202 (2005-07-21)
We investigated the stereoselective kinetic disposition and metabolism of metoprolol (MET) in rats. The racemic MET (15 mg/kg) was given by oral gavage and blood samples were collected from 0 to 10h (n=6 at each time point). The enantiomeric concentrations



Global Trade Item Number

SKUGTIN
80073-25MG04061832974408