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Merck
CN

80621

Piperazine

BioUltra, anhydrous, ≥99.0% (T)

Synonym(s):

1,4-Diazacyclohexane, Diethylenediamine

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About This Item

Empirical Formula (Hill Notation):
C4H10N2
CAS Number:
110-85-0
Molecular Weight:
86.14
NACRES:
NA.25
PubChem Substance ID:
329769002
eCl@ss:
39160301
UNSPSC Code:
12161700
EC Number:
203-808-3
MDL number:
MFCD00005953
Beilstein/REAXYS Number:
102555

Key Documents

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Product Name

Piperazine, BioUltra, anhydrous, ≥99.0% (T)

InChI key

GLUUGHFHXGJENI-UHFFFAOYSA-N

InChI

1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2

SMILES string

C1CNCCN1

vapor pressure

0.8 mmHg ( 20 °C)

product line

BioUltra

assay

≥99.0% (T)

form

solid

expl. lim.

14 %

impurities

insoluble matter, passes filter test
≤1% water

pH

11.0-12.5 (25 °C, 0.1 M in H2O)

bp

145-146 °C (lit.)

mp

109-112 °C (lit.)

solubility

H2O: 0.1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.1 M in H2O

UV absorption

λ: 260 nm Amax: 0.035
λ: 280 nm Amax: 0.010

Quality Level

200

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Related Categories

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Flam. Sol. 1 - Repr. 2 - Resp. Sens. 1B - Skin Corr. 1B - Skin Sens. 1B

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCP0377
BCCN6705
BCCN6704
BCCN3417
BCCL6236

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Mitsunori Kono et al.
Bioorganic & medicinal chemistry, 21(1), 28-41 (2012-12-12)
A series of piperazine ureas was designed, synthesized, and evaluated for their potential as novel orally available fatty acid amide hydrolase (FAAH) inhibitors that are therapeutically effective against pain. We carried out an optimization study of the lead compound 3
R A Lovell
The Veterinary clinics of North America. Small animal practice, 20(2), 453-468 (1990-03-01)
Review of all reports involving anthelmintics in dogs and cats to the IAPIC between January 1, 1986 and August 10, 1988, revealed that ivermectin (extra-label use) and piperazine accounted for over 50% of the calls assessed as toxicoses and suspected
Janie Sheridan et al.
Drug and alcohol review, 26(3), 335-343 (2007-04-25)
In this Harm Reduction Digest Sheridan, Butler, Wilkins and Russell address the emergent phenomenon of so-called 'legal party pills' which have become a significant drug issue in New Zealand and elsewhere. Although banned in a number of countries, they are
Yinghui Mo et al.
Environmental science & technology, 46(24), 13253-13261 (2012-12-05)
Carboxyls are inherent functional groups of thin-film composite polyamide nanofiltration (NF) membranes, which may play a role in membrane performance and fouling. Their surface presence is attributed to incomplete reaction of acyl chloride monomers during the membrane active layer synthesis
Slavka Hamulakova et al.
European journal of medicinal chemistry, 55, 23-31 (2012-07-24)
New tacrine derivatives 5a-d, 6a-d with piperazino-ethyl spacer linked with corresponding secondary amines and tacrine homodimer 8 were synthesized and tested as cholinesterase inhibitors on human acetylcholinesterase (hAChE) and human plasmatic butyrylcholinesterase (hBChE). In most cases the majority of synthesized
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