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Merck
CN

84850

Sebacoyl chloride

purum, ≥95.0% (GC)

Synonym(s):

Sebacyl chloride

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About This Item

Linear Formula:
ClCO(CH2)8COCl
CAS Number:
Molecular Weight:
239.14
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
203-843-4
Beilstein/REAXYS Number:
1365665
MDL number:
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grade

purum

Quality Level

assay

≥95.0% (GC)

form

liquid

refractive index

n20/D 1.468

bp

168 °C/12 mmHg (lit.)

mp

−5-−3 °C (lit.)

density

1.119 g/mL at 20 °C, 1.121 g/mL at 25 °C (lit.)

SMILES string

ClC(=O)CCCCCCCCC(Cl)=O

InChI

1S/C10H16Cl2O2/c11-9(13)7-5-3-1-2-4-6-8-10(12)14/h1-8H2

InChI key

WMPOZLHMGVKUEJ-UHFFFAOYSA-N

General description

Sebacoyl chloride is a light yellow, pungent odored di-acryl chloride. It is soluble in hydrocarbons and ethers.It hydrolyzes in water, releasing hydrogen chloride.

Application

Sebacoyl chloride may be used along with hexamethylenediamine, during Schotten -Baumann reactions, to produce a polyamide (eg.Nylon 6,10).


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pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

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Zhe Gong et al.
ACS biomaterials science & engineering, 6(11), 6331-6343 (2021-01-16)
Despite decades of research, spinal cord injury (SCI) still causes irreparable damage to the human body. Key challenges that hinder the regeneration and extension of neurons following SCI must be overcome, including the overexpressed glial scar formation and strong inflammatory
Zhenhua Xu et al.
International journal of pharmaceutics, 426(1-2), 182-192 (2012-01-24)
In this study we describe a novel polymer, mPPS-FA, synthesized as a potential gene transfer vector. To complete mPPS-FA, folic acid was conjugated to a backbone (named mPPS) consisting of a copolymer of methyl PEG-2000, PEI-600, and sebacoyl chloride. (1)H
D Poncelet et al.
Journal of microencapsulation, 11(1), 31-40 (1994-01-01)
A microencapsulation technique is proposed involving the formation of a polyethyleneimine (PEI) membrane crosslinked by an acid dichloride. The membranes were formed at pH 8 in a non-polar solvent, conditions which are better suited for the encapsulation of biocatalysts or



Global Trade Item Number

SKUGTIN
84850-100ML04061833008256
84850-500ML04061837831867
84850-25ML04061833008263