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Merck
CN

85432

Silylating mixture II according to Horning

derivatization grade (GC derivatization), LiChropur

Synonym(s):

N,O-Bis(trimethylsilyl)acetamide – chlorotrimethylsilane – 1-(trimethylsilyl)imidazole mixture, BSA+TMCS+TMSI 3:2:3, TMSIm/BSA/TMCS 3/3/2 (v/v/v)

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About This Item

CAS Number:
NACRES:
NA.22
UNSPSC Code:
23151816
MDL number:
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InChI

1S/C8H21NOSi2.C6H12N2Si.C3H9ClSi/c1-8(9-11(2,3)4)10-12(5,6)7;1-9(2,3)8-5-4-7-6-8;1-5(2,3)4/h1-7H3;4-6H,1-3H3;1-3H3

InChI key

QSBHIAMPMUWWFU-UHFFFAOYSA-N

grade

derivatization grade (GC derivatization)

form

liquid

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

storage temp.

2-8°C

Quality Level

Application

Learn more in the Product Information

Other Notes

N,O-Bis(trimethylsilyl)acetamide : chlorotrimethylsilane : 1-(trimethylsilyl)imidazole = 3:3:2 (v/v/v)
One of the most powerful, general silylating mixture

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

39.2 °F - closed cup

flash_point_c

4.0 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品
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J. Heberle et al.
Silylating Agents, 2nd ed. (1995)
Conversion of steroids to trimethylsilyl derivatives for gas phase analytical studies: reactions of silylating reagents.
E M Chambaz et al.
Analytical biochemistry, 30(1), 7-24 (1969-07-01)

Articles

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

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