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Merck
CN

87117

Nervonic acid

analytical standard

Synonym(s):

cis-15-Tetracosenoic acid, Selacholeic acid

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About This Item

Linear Formula:
CH3(CH2)7CH=CH(CH2)13COOH (cis)
CAS Number:
Molecular Weight:
366.62
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1728551
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Product Name

Nervonic acid, analytical standard

InChI

1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9-

SMILES string

CCCCCCCC\C=C/CCCCCCCCCCCCCC(O)=O

InChI key

GWHCXVQVJPWHRF-KTKRTIGZSA-N

grade

analytical standard

assay

≥99.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

42-43 °C (lit.)

format

neat

functional group

carboxylic acid

shipped in

ambient

storage temp.

−20°C

Quality Level

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Application

Nervonic acid may be used as an analytical reference standard for the determination of nervonic acid in:
  • Berry seed extract samples by gas chromatography equipped with mass spectrometer detector (GC-MSD).
  • Human blood by isotope-dilution gas chromatography-negative chemical ionization-mass spectrometry (ID-GC-NCI-MS).
  • Human plasma samples employed in the clinical smoking cessation study by GC combined with time-of-flight mass spectrometry operating under the electron ionization (EI) mode.
  • Brain tissue samples by GC-MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Nervonic acids are the products of desaturation and elongation processes of various fatty acids such as palmitic acid, stearic acid, oleic acid, etc.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

230.0 °F - closed cup

flash_point_c

110 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Fatty Acids Analysis Using Gas Chromatography-Mass Spectrometer Detector (GC/MSD)-Method Validation Based on Berry Seed Extract Samples.
Mazurek B, et al.
Food Analytical Methods, 10(8), 2868-2880 (2017)
A fully validated GC-TOF-MS method for the quantification of fatty acids revealed alterations in the metabolic profile of fatty acids after smoking cessation.
Goettel M, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1041(8), 141-150 (2017)
Quantitation of trans-fatty acids in human blood via isotope dilution-gas chromatography-negative chemical ionization-mass spectrometry.
Kuiper HC, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1076(8), 35-43 (2018)
Jiun-Rong Chen et al.
The Journal of nutritional biochemistry, 15(8), 467-472 (2004-08-11)
Nutritional factors may be relative to attention-deficit hyperactive disorder (ADHD), although the pathogenic mechanism is still unknown. Based on the work of others, we hypothesized that children with ADHD have altered dietary patterns and fatty acid metabolism. Therefore, the aim
Demetris Bitsanis et al.
The Journal of nutrition, 135(11), 2566-2571 (2005-10-28)
The aim of this study was to determine whether the high concentration of arachidonic acid (AA) in term placentae accumulates during pregnancy or is an inherent characteristic of placental lipids. We investigated the lipid content and fatty acid composition of

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