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Supelco

Tetrahexylammonium bromide

suitable for ion pair chromatography, LiChropur™, ≥99.0% (AT)

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Linear Formula:
[CH3(CH2)5]4N(Br)
CAS Number:
4328-13-6
Molecular Weight:
434.58
Beilstein:
3637302
EC Number:
224-363-1
MDL number:
MFCD00011858
PubChem Substance ID:
329769522
NACRES:
NB.21

description

cationic

Quality Level

100

Assay

≥99.0% (AT)

form

crystals

quality

LiChropur™

technique(s)

ion pair chromatography: suitable

mp

99-100 °C (lit.)

λ

10 % in methanol

UV absorption

λ: 240 nm Amax: 0.06
λ: 250 nm Amax: 0.04
λ: 260 nm Amax: 0.03
λ: 500 nm Amax: 0.03

suitability

corresponds to standard for filter test

SMILES string

[Br-].CCCCCC[N+](CCCCCC)(CCCCCC)CCCCCC

InChI

1S/C24H52N.BrH/c1-5-9-13-17-21-25(22-18-14-10-6-2,23-19-15-11-7-3)24-20-16-12-8-4;/h5-24H2,1-4H3;1H/q+1;/p-1

InChI key

SYZCZDCAEVUSPM-UHFFFAOYSA-M

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General description

The utilization of ion-pairing reagents as mobile phase additives allows the elution of ionic and highly polar substances using reversed phase HPLC columns. The purity of mobile phase additives is a prime factor to their successful application. Sigma-Aldrich offers an outstanding collection of tailor-made reagents for anionic (quaternary ammonium and phosphonium salts) and cationic (alkanesulfonates) analyzes. All mobile phase additives are rigorously tested with special emphasis on the requirements of modern reversed phase HPLC:

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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The effects of tetrahexylammonium chloride on calcium mobilization from cerebellar microsomes.
L G Sayers et al.
Biochemical Society transactions, 21(2), 105S-105S (1993-05-01)
Zeynep S Teksin et al.
Journal of controlled release : official journal of the Controlled Release Society, 116(1), 50-57 (2006-10-20)
Parallel Artificial Membrane Permeability Assay (PAMPA) is a method to screen drug candidates for membrane permeability. The objective was to characterize the transport of a model weak base, metoprolol, across a three lipid-component PAMPA system (denoted A-PAMPA, for anionic-PAMPA) and
K M Sunasara et al.
Biotechnology progress, 17(5), 897-906 (2001-10-06)
This work investigates the utility of RPLC displacement chromatography for the purification of recombinant brain derived neurotrophic factor (rHu-BDNF) from its variants and E. coli. protein (ECP) impurities. The closely associated variants (six in total) differ by one amino acid
L Zhang et al.
The Journal of pharmacology and experimental therapeutics, 288(3), 1192-1198 (1999-02-23)
Polyspecific organic cation transporters in epithelia play an important role in the elimination of many endogenous bioactive amines and therapeutically important drugs. Recently, the first human organic cation transporter (hOCT1) was cloned from liver. The purpose of the current study
Y Uyama et al.
Pflugers Archiv : European journal of physiology, 426(5), 363-370 (1994-03-01)
Effects of tetraalkylammonium ions, having tetraalkyl chains of increasing length from ethyl to octyl, on inositol-trisphosphate (InsP3)-induced Ca2+ release and contractile mechanics were examined in guinea-pig skinned ileal smooth muscle longitudinal strips. Although tetrahexylammonium ions (THexA) appeared to be the
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