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Merck
CN

89650

p-Toluidine hydrochloride

purum, ≥99.0% (AT)

Synonym(s):

4-Methylaniline hydrochloride

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About This Item

Linear Formula:
CH3C6H4NH2 · HCl
CAS Number:
Molecular Weight:
143.61
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-740-8
Beilstein/REAXYS Number:
3557540
MDL number:
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Product Name

p-Toluidine hydrochloride, purum, ≥99.0% (AT)

InChI key

JQKBUTDZZRGQDR-UHFFFAOYSA-N

InChI

1S/C7H9N.ClH/c1-6-2-4-7(8)5-3-6;/h2-5H,8H2,1H3;1H

SMILES string

Cl[H].Cc1ccc(N)cc1

grade

purum

assay

≥99.0% (AT)

form

crystals

mp

243-245 °C (lit.)

Quality Level

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Related Categories

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Takeshi Toyoda et al.
Archives of toxicology, 93(3), 753-762 (2019-01-19)
Although aromatic amines are widely used as raw materials for dyes, some of them have been concerned about carcinogenicity in the urinary bladder. We examined early changes in histopathology and the formation of γ-H2AX, a biomarker of DNA damage, in
W J Brock et al.
Toxicology letters, 54(2-3), 317-325 (1990-12-01)
The in vivo covalent binding of ortho- and para-toluidine (OT and PT) to rat hepatic macromolecules was investigated to determine if a relationship exists between the degree of binding for each isomer and its carcinogenic potency. The ortho-isomer has been
D R Doerge et al.
Chemical research in toxicology, 4(5), 556-560 (1991-09-01)
The metabolism of three arylamine substrates by H2O2 in the presence of each of the peroxidative enzymes chloroperoxidase (CPX) and pea seed peroxygenase (PSM) was conducted with normal H2O2 and with 18O-labeled H2O2. The resulting C-nitroso aromatic metabolites were examined
Jingyan Zhang et al.
Journal of colloid and interface science, 316(2), 796-802 (2007-10-02)
The kinetics and mechanism of sphere-to-rod transitions of sodium alkyl sulfate micelles induced by hydrotropic salt, p-toluidine hydrochloride (PTHC), were investigated by stopped-flow with light scattering detection. Spherical sodium dodecyl sulfate (SDS) micelles transform into short ellipsoidal shapes at low
Hao Wu et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 67(3-4), 976-979 (2007-02-03)
The molecular interactions between aniline, p-toluidines, benzidine and p-phenylenediamine as electron donors and 7,7,8,8-tetracyanoquinodimethane (TCNQ) as acceptor have been investigated by spectrophotometric method. Different variables affecting the reaction were studies and optimized. At the optimum reaction conditions Beer's law was

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