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Merck
CN

89921

(±)-2,4-Dihydroxybutyric acid lithium salt

≥95.0% (GC)

Synonym(s):

2,4-Dihydroxybutanoic acid lithium salt

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About This Item

Empirical Formula (Hill Notation):
C4H8O4
CAS Number:
Molecular Weight:
120.10
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.24
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Quality Level

assay

≥95.0% (GC)

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

OC(CCO)C(=O)O

InChI

1S/C4H8O4/c5-2-1-3(6)4(7)8/h3,5-6H,1-2H2,(H,7,8)

InChI key

UFYGCFHQAXXBCF-UHFFFAOYSA-N

Biochem/physiol Actions

Various cases of succinic semialdehyde dehydrogenase deficiency have shown consistently increased amounts of this metabolite, while 2,4-dihydroxybutanoic acid is usually absent in normal human urine extracts or in only trace constituents in neonates.


Storage Class

11 - Combustible Solids

wgk

WGK 3



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M Orešič et al.
Translational psychiatry, 1, e57-e57 (2011-01-01)
Mild cognitive impairment (MCI) is considered as a transition phase between normal aging and Alzheimer's disease (AD). MCI confers an increased risk of developing AD, although the state is heterogeneous with several possible outcomes, including even improvement back to normal
G K Brown et al.
Journal of inherited metabolic disease, 10(4), 367-375 (1987-01-01)
In addition to the previously reported abnormalities, urine extracts from three cases of succinic semialdehyde dehydrogenase deficiency have shown consistently increased amounts of 2,4-dihydroxybutyric acid, and its lactone, and 3-hydroxypropionic acid, metabolites related to the alpha-oxidation of 4-hydroxybutyric acid. Threo-
Minna Hartonen et al.
Journal of chromatography. A, 1293, 142-149 (2013-05-07)
Comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (GC×GC-TOFMS) was applied in the quantification and identification of organic compounds in patient-matched human cerebrospinal fluid (CSF) and serum samples. Concentrations of 21 amino and hydroxyl acids varied from 0.04 to 77ng/μl in CSF



Global Trade Item Number

SKUGTIN
89921-50MG04061833416099
89921-10MG04061833077368